Hôpital Cardiologique du Haut-Lévêque and Université de Bordeaux, IHU LIRYC ANR-10-IAHU-04, Bordeaux-Pessac, France.
Hôpital Cardiologique du Haut-Lévêque and Université de Bordeaux, IHU LIRYC ANR-10-IAHU-04, Bordeaux-Pessac, France.
JACC Clin Electrophysiol. 2018 Jan;4(1):33-45. doi: 10.1016/j.jacep.2017.07.018. Epub 2017 Sep 27.
The purpose of this study was to describe and identify useful electrocardiographic characteristics to help identify the mechanism of atrial tachycardia (AT) occurring after persistent atrial fibrillation (PsAF) ablation.
Electrocardiographic analysis to help identify the mechanism of AT after PsAF ablation is much limited by the fact that remodeling and ablation alter the normal activation pattern.
All consecutive patients who underwent mapping and ablation of AT after PsAF ablation were included. Surface P waves were analyzed during higher (>2:1) grades of atrioventricular block.
One hundred ninety-six ATs with visible P waves were identified in 127 patients (macro-re-entry in 57%, centrifugal AT in 43%). One-third displayed low-voltage P waves (≤0.1 mV). An isoelectric line >80 ms was more common in centrifugal compared with macro-re-entrant AT (47% vs. 24%; p < 0.001), but its positive predictive value was limited (60%). A minority of peritricuspid ATs displayed the classic saw-tooth pattern (27% [n = 22]). However, the "precordial transition" (a gradual transition from an upright component in lead V to a negative component with progression across the precordium) remained often observed and specifically identified peritricuspid AT (specificity, 98%; sensitivity, 59%). Only 2 unique features could help identify perimitral AT (n = 60). First, the presence of a negative or negative-positive P-wave in any of leads V to V identified perimitral AT with 97% specificity and 30% sensitivity. Second, a "notched" negative component at the beginning of a positive P-wave in the inferior leads specifically identified clockwise perimitral AT (specificity, 98%; sensitivity, 25%).
Only few unique electrocardiographic characteristics help identify the mechanism of AT after PsAF ablation. Knowledge of these characteristics may aid in planning and performing ablation.
本研究旨在描述和确定有用的心电图特征,以帮助识别持续性心房颤动(PsAF)消融后发生的房性心动过速(AT)的机制。
心电图分析在帮助识别 PsAF 消融后 AT 的机制方面受到很大限制,这是因为重构和消融改变了正常的激活模式。
纳入所有在 PsAF 消融后进行 AT 标测和消融的连续患者。在较高(>2:1)房室传导阻滞分级时分析体表 P 波。
在 127 例患者中发现了 196 次可见 P 波的 AT(大环折返性心动过速占 57%,离心性 AT 占 43%)。三分之一的 P 波低电压(≤0.1 mV)。与大环折返性心动过速相比,离心性 AT 中存在等电位线>80 ms 的情况更为常见(47%比 24%;p<0.001),但其阳性预测值有限(60%)。少数三尖瓣环周 AT 表现出典型的锯齿状形态(27%[n=22])。然而,“心前区过渡”(从 V 导联的直立成分到心前区进展的负向成分的逐渐过渡)仍然经常观察到,并特异性识别三尖瓣环周 AT(特异性,98%;敏感性,59%)。只有 2 个独特的特征可以帮助识别二尖瓣环周 AT(n=60)。首先,V 至 V 导联任何导联中出现负向或负正向 P 波可特异性识别二尖瓣环周 AT,特异性为 97%,敏感性为 30%。其次,下壁导联中正向 P 波起始时的“切迹”负向成分特异性识别顺时针二尖瓣环周 AT(特异性,98%;敏感性,25%)。
只有少数独特的心电图特征有助于识别 PsAF 消融后 AT 的机制。了解这些特征可能有助于计划和进行消融。