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[球囊扩张术后反复复发——扩张还是手术?]

[Repeated recurrences after balloon dilatation--dilate or operate?].

作者信息

Vallbracht C, Kober G, Kunkel B, Hopf R, Sievert H, Kaltenbach M

机构信息

Zentrum der Inneren Medizin, Abteilung für Kardiologie, Johann-Wolfgang-Goethe-Universität, Frankfurt.

出版信息

Z Kardiol. 1987 Jul;76(7):428-32.

PMID:2960089
Abstract

In a total of 333 patients who had undergone a first successful transluminal coronary angioplasty (TCA) of a single stenosis in a native coronary vessel, restenosis occurred in 15% (follow-up angiography was performed in 94% of these patients). The restenosis rate was higher in bypass stenoses (45%) and in reopened vessels (54%). Repeat dilatation of restenoses showed a high primary success rate (93%) and only a few complications (2%). In this group, recurrent restenosis was observed in 33% of patients. Thirteen patients with recurrent restenoses (11 patients with two recidivations and two patients with three) underwent a total of 41 dilatation attempts. The degree of the recurrent stenosis (prior to the first TCA: 89%; prior to the second: 82%; prior to the third: 74%), the number of eccentric stenoses (8; 7; 5, respectively) and the length of the stenotic obstruction (5.2 mm; 4.7 mm; 4.3 mm, respectively) decreased. Accordingly, exercise tolerance was improved (99 W, 133 W, 146 W). To date, follow-up angiography and functional investigations have been performed in 11 out of 13 patients. Good long-term results have been observed in eight patients and another restenosis in three. It is concluded that repeat angioplasty is a reasonable therapeutic approach also in patients with recurrent restenosis.

摘要

在总共333例首次成功对自身冠状动脉单处狭窄进行经皮腔内冠状动脉成形术(TCA)的患者中,15%发生了再狭窄(94%的患者进行了随访血管造影)。搭桥血管狭窄(45%)和再通血管(54%)的再狭窄率更高。对再狭窄进行重复扩张显示出较高的初次成功率(93%)且仅有少数并发症(2%)。在该组中,33%的患者观察到复发性再狭窄。13例复发性再狭窄患者(11例复发两次,2例复发三次)共进行了41次扩张尝试。复发性狭窄的程度(首次TCA前:89%;第二次前:82%;第三次前:74%)、偏心性狭窄的数量(分别为8处、7处、5处)以及狭窄阻塞的长度(分别为5.2毫米、4.7毫米、4.3毫米)均有所降低。相应地,运动耐量得到改善(分别为99瓦、133瓦、146瓦)。迄今为止,13例患者中有11例进行了随访血管造影和功能检查。8例患者观察到良好的长期结果,3例再次发生再狭窄。得出的结论是,对于复发性再狭窄患者,重复血管成形术也是一种合理的治疗方法。

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