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食管压力监测:为何、何时以及如何?

Esophageal pressure monitoring: why, when and how?

机构信息

Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.

出版信息

Curr Opin Crit Care. 2018 Jun;24(3):216-222. doi: 10.1097/MCC.0000000000000494.

Abstract

PURPOSE OF REVIEW

Esophageal manometry has shown its usefulness to estimate transpulmonary pressure, that is lung stress, and the intensity of spontaneous effort in patients with acute respiratory distress syndrome. However, clinical uptake of esophageal manometry in ICU is still low. Thus, the purpose of review is to describe technical tips to adequately measure esophageal pressure at the bedside, and then update the most important clinical applications of esophageal manometry in ICU.

RECENT FINDINGS

Each esophageal balloon has its own nonstressed volume and it should be calibrated properly to measure pleural pressure accurately: transpulmonary pressure calculated on absolute esophageal pressure reflects values in the lung regions adjacent to the esophageal balloon (i.e. dependent to middle lung). Inspiratory transpulmonary pressure calculated from airway plateau pressure and the chest wall to respiratory system elastance ratio reasonably reflects lung stress in the nondependent 'baby' lung, at highest risk of hyperinflation. Also esophageal pressure can be used to detect and minimize patient self-inflicted lung injury.

SUMMARY

Esophageal manometry is not a complicated technique. There is a large potential to improve clinical outcome in patients with acute respiratory distress syndrome, acting as an early detector of risk of lung injury from mechanical ventilation and vigorous spontaneous effort.

摘要

目的综述

食管测压在估计跨肺压(即肺应力)和急性呼吸窘迫综合征患者自主努力强度方面显示出其有用性。然而,食管测压在 ICU 中的临床应用仍然很低。因此,本综述的目的是描述在床边充分测量食管压力的技术要点,然后更新食管测压在 ICU 中的最重要临床应用。

最近的发现

每个食管球囊都有自己的无应力容积,应进行适当校准,以准确测量胸膜压力:基于绝对食管压力计算的跨肺压反映了与食管球囊相邻的肺区(即依赖于中肺)的压力。从气道平台压和胸壁-呼吸系统顺应性比计算得出的吸气跨肺压合理地反映了非依赖性“婴儿”肺中的肺应力,该肺最容易发生过度充气。食管压力也可用于检测和最小化患者的自伤性肺损伤。

总结

食管测压不是一项复杂的技术。它有很大的潜力可以改善急性呼吸窘迫综合征患者的临床预后,作为机械通气和剧烈自主努力导致肺损伤风险的早期检测手段。

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