小儿圆锥角膜的角膜交联术综述
Corneal Cross-Linking for Pediatric Keratcoconus Review.
作者信息
Perez-Straziota Claudia, Gaster Ronald N, Rabinowitz Yaron S
机构信息
Department of Ophthalmology, University of Southern California, Los Angeles, CA.
Cornea Eye Institute, Beverly Hills, CA.
出版信息
Cornea. 2018 Jun;37(6):802-809. doi: 10.1097/ICO.0000000000001579.
Abstract
PURPOSE
To comprehensively review the available published literature for cross-linking in the pediatric population.
METHODS
Review of the literature published in English in PubMed.
RESULTS
Two hundred ten publications were considered. One hundred fifteen were considered relevant to this review.
CONCLUSIONS
Studies of cross-linking in pediatric patients are sparse, with relatively short follow-up times, and mostly on small groups of patients. Treatment with cross-linking halts progression of keratoconus in the pediatric population, and early treatment seems to be cost-effective compared with later penetrating keratoplasty. Long-term effects and regression rates remain unclear, and further studies are needed in this population.
摘要
目的
全面回顾已发表的有关儿科人群交联治疗的文献。
方法
检索PubMed上发表的英文文献。
结果
共筛选出210篇出版物。其中115篇被认为与本综述相关。
结论
儿科患者交联治疗的研究较少，随访时间相对较短，且大多针对小样本患者群体。交联治疗可阻止儿科圆锥角膜患者病情进展，与后期穿透性角膜移植术相比，早期治疗似乎更具成本效益。长期效果和回退率仍不明确，该人群需要进一步研究。
相似文献
1
Corneal Cross-Linking for Pediatric Keratcoconus Review.小儿圆锥角膜的角膜交联术综述
Cornea. 2018 Jun;37(6):802-809. doi: 10.1097/ICO.0000000000001579.
2
Long-term results of cornea collagen cross-linking with riboflavin for keratoconus.角膜交联术联合核黄素治疗圆锥角膜的长期疗效。
Indian J Ophthalmol. 2013 Aug;61(8):433-4. doi: 10.4103/0301-4738.116072.
3
Crosslinking for recurrent keratoconus.复发性圆锥角膜的交联治疗。
Ophthalmology. 2012 Apr;119(4):878-878.e2. doi: 10.1016/j.ophtha.2011.11.007.
4
Safety of corneal collagen cross-linking with UV-A and riboflavin in progressive keratoconus.渐进性圆锥角膜中使用紫外线 A 和核黄素进行角膜胶原交联的安全性。
Cornea. 2010 Apr;29(4):409-11. doi: 10.1097/ICO.0b013e3181bd9f8c.
5
Corneal collagen cross-linking.角膜胶原交联
Am J Ophthalmol. 2012 Sep;154(3):423-424.e1. doi: 10.1016/j.ajo.2012.05.005.
6
Newer protocols and future in collagen cross-linking.新型方案和交联胶原的未来。
Indian J Ophthalmol. 2013 Aug;61(8):425-7. doi: 10.4103/0301-4738.116076.
7
Current status of accelerated corneal cross-linking.加速角膜交联术的现状。
Indian J Ophthalmol. 2013 Aug;61(8):428-9. doi: 10.4103/0301-4738.116075.
8
Keratoconus and corneal collagen cross-linking.圆锥角膜与角膜胶原交联
Indian J Ophthalmol. 2013 Aug;61(8):380. doi: 10.4103/0301-4738.116049.
9
Corneal regularization following customized corneal collagen cross-linking.定制角膜胶原交联术后的角膜规则化
Indian J Ophthalmol. 2018 Sep;66(9):1310-1311. doi: 10.4103/ijo.IJO_1101_17.
10
Corneal collagen cross-linking with riboflavin and ultraviolet-A irradiation in patients with thin corneas.薄角膜患者中核黄素与紫外线A照射的角膜胶原交联。
Am J Ophthalmol. 2012 May;153(5):1002; author reply 1002-3. doi: 10.1016/j.ajo.2012.01.014.
引用本文的文献
1
Brittle Cornea Syndrome: Molecular Diagnosis and Management.脆性角膜综合征：分子诊断与管理
Diagnostics (Basel). 2025 Jun 24;15(13):1596. doi: 10.3390/diagnostics15131596.
2
Management of corneal melting after collagen cross-linking for keratoconus: a case report and a review of the literature.交联治疗圆锥角膜后角膜融解的处理：病例报告及文献复习。
BMC Ophthalmol. 2024 Mar 25;24(1):131. doi: 10.1186/s12886-024-03400-1.
3
Corneal biomechanics and diagnostics: a review.角膜生物力学与诊断：综述
Int Ophthalmol. 2024 Mar 13;44(1):132. doi: 10.1007/s10792-024-03057-1.
4
Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes.用于进行性圆锥角膜的经上皮加速交联：中期治疗结果的批判性分析
Clin Ophthalmol. 2024 Feb 8;18:393-407. doi: 10.2147/OPTH.S450916. eCollection 2024.
5
Pediatric keratoconus epidemiology: a systematic scoping review.小儿圆锥角膜流行病学：一项系统的范围综述
Int Ophthalmol. 2024 Feb 12;44(1):69. doi: 10.1007/s10792-024-03010-2.
6
Paediatric cornea crosslinking current strategies: A review.小儿角膜交联的当前策略：综述
Adv Ophthalmol Pract Res. 2022 Nov 25;3(2):55-62. doi: 10.1016/j.aopr.2022.11.002. eCollection 2023 May-Jun.
7
Factors Associated With Receipt of Crosslinking for Keratoconus.与圆锥角膜交联治疗相关的因素。
Cornea. 2024 Feb 1;43(2):214-220. doi: 10.1097/ICO.0000000000003353. Epub 2023 Jul 27.
8
The Keratectasia Volume (KEV) in Corneal Topography to Evaluate the Effect of Corneal Collagen Cross-linking in Pediatric Keratoconus.角膜地形图中的角膜扩张量（KEV）评估儿童圆锥角膜角膜胶原交联的效果。
J Digit Imaging. 2023 Aug;36(4):1752-1759. doi: 10.1007/s10278-021-00515-5. Epub 2023 Apr 14.
9
Photoactivated Chromophore Corneal Collagen Cross-Linking for Infectious Keratitis (PACK-CXL)-A Comprehensive Review of Diagnostic and Prognostic Factors Involved in Therapeutic Indications and Contraindications.用于感染性角膜炎的光活化发色团角膜胶原交联术（PACK-CXL）——对治疗适应证和禁忌证中涉及的诊断及预后因素的全面综述
J Pers Med. 2022 Nov 16;12(11):1907. doi: 10.3390/jpm12111907.
10
Pediatric Crosslinking: Current Protocols and Approach.儿科交联：当前方案与方法
Ophthalmol Ther. 2022 Jun;11(3):983-999. doi: 10.1007/s40123-022-00508-9. Epub 2022 Apr 28.
本文引用的文献
1
Corneal Collagen Cross-Linking With Riboflavin and Ultraviolet A Light for Pediatric Keratoconus: Ten-Year Results.核黄素和紫外线A光角膜交联治疗儿童圆锥角膜：十年结果
Cornea. 2018 May;37(5):560-566. doi: 10.1097/ICO.0000000000001505.
2
Prevalence of keratoconus in paediatric patients in Riyadh, Saudi Arabia.沙特阿拉伯利雅得儿科患者圆锥角膜的患病率。
Br J Ophthalmol. 2018 Oct;102(10):1436-1441. doi: 10.1136/bjophthalmol-2017-311391. Epub 2018 Jan 3.
3
Microbial Keratitis After Accelerated Corneal Collagen Cross-Linking in Keratoconus.圆锥角膜加速角膜胶原交联术后的微生物性角膜炎
Cornea. 2018 Feb;37(2):162-167. doi: 10.1097/ICO.0000000000001439.
4
Cost-Effectiveness Analysis of Corneal Collagen Crosslinking for Progressive Keratoconus.角膜交联术治疗进展性圆锥角膜的成本效果分析。
Ophthalmology. 2017 Oct;124(10):1485-1495. doi: 10.1016/j.ophtha.2017.04.011. Epub 2017 May 19.
5
United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment.美国角膜交联治疗圆锥角膜多中心临床试验。
Ophthalmology. 2017 Sep;124(9):1259-1270. doi: 10.1016/j.ophtha.2017.03.052. Epub 2017 May 7.
6
Corneal Collagen Cross-Linking in the Management of Keratoconus in Canada: A Cost-Effectiveness Analysis.加拿大圆锥角膜管理中的角膜胶原交联：成本效益分析。
Ophthalmology. 2017 Aug;124(8):1108-1119. doi: 10.1016/j.ophtha.2017.03.019. Epub 2017 Apr 27.
7
Accelerated corneal collagen cross-linking in pediatric keratoconus: One year study.儿童圆锥角膜的加速角膜胶原交联：一年研究
Saudi J Ophthalmol. 2017 Jan-Mar;31(1):11-18. doi: 10.1016/j.sjopt.2017.01.002. Epub 2017 Jan 25.
8
Prevalence of Eyelid Laxity and its Association with Ophthalmic Findings and Disease Severity in Patients with Keratoconus.圆锥角膜患者眼睑松弛的患病率及其与眼科检查结果和疾病严重程度的关系
Eur J Ophthalmol. 2017 Nov 8;27(6):670-674. doi: 10.5301/ejo.5000937.
9
Corneal Collagen Cross-Linking for Keratoconus in Pediatric Patients-Long-Term Results.儿童圆锥角膜的角膜胶原交联术——长期结果
Cornea. 2017 Feb;36(2):138-143. doi: 10.1097/ICO.0000000000001102.
10
Trends in Corneal Transplantation in Keratoconus.圆锥角膜角膜移植的趋势
Cornea. 2017 Feb;36(2):131-137. doi: 10.1097/ICO.0000000000001083.
Zotero 插件