Department of Obstetrics and Gynecology, University of Miami Miller School of Medicine, Miami, FL.
Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.
J Low Genit Tract Dis. 2018 Oct;22(4):336-339. doi: 10.1097/LGT.0000000000000396.
The aim of the study was to assess risk factors for anal human papillomavirus (HPV) infection and anal dysplasia among a cohort of transgender women (TGW).
A retrospective chart review was conducted based on electronic medical records of TGW patients seen in the University of Miami Health System between 2010 and 2016. Outcome measures included risk factors of anal dysplasia, including HIV infection, receptive anal intercourse, and smoking history. Descriptive statistical analysis and χ testing were used.
Sixty-nine TGW patients' charts were reviewed. Patients' ages ranged from 18 to 72 (mean = 38 [15]). Twenty-two (30%) were older than 50 years; 10 (15%) were black/African descent; 20 (29%) reported a smoking history; 6 (9%) were HIV positive, and 28 (72%) among those with known partner preference (n = 39) reported male partners. Male partner preference was significantly associated with being black/African descent (p = .009) and being single (p = .048). Older age was significantly associated with HIV-positive status (p = .023). The average number of risk factors per person was 2.10 (0.97). Sixty-one years or older had the highest average number of risk factors (2.90 [0.88]).
Because rates of HIV, dangerous sexual behaviors, and other risk factors for anal dysplasia continue to persist among TGW, this study reinforces the need to increase the focus on anal health in the care of TGW and the need for further research to guide patient care and anal dysplasia screening strategies among those individuals.
本研究旨在评估 transgender women（TGW）队列中肛门人乳头瘤病毒（HPV）感染和肛门发育不良的危险因素。
对 2010 年至 2016 年间在迈阿密大学健康系统就诊的 TGW 患者的电子病历进行回顾性图表审查。结局指标包括肛门发育不良的危险因素，包括 HIV 感染、接受性肛交和吸烟史。采用描述性统计分析和 χ 检验。
共回顾了 69 名 TGW 患者的图表。患者年龄 18-72 岁，平均 38（15）岁。22 例（30%）年龄大于 50 岁；10 例（15%）为黑种人/非裔；20 例（29%）有吸烟史；6 例（9%）HIV 阳性，28 例（72%）已知有性伴侣的患者（n = 39）报告有男性伴侣。性伴侣偏好与黑种人/非裔（p =.009）和单身（p =.048）显著相关。年龄较大与 HIV 阳性状态显著相关（p =.023）。每人平均危险因素数为 2.10（0.97）。61 岁或以上的人平均有 2.90（0.88）个危险因素。
由于 HIV、危险性行为和其他肛门发育不良的危险因素在 TGW 中继续存在，本研究再次强调需要增加对 TGW 肛门健康的关注，并需要进一步研究，以指导这些人群的患者护理和肛门发育不良筛查策略。
