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[过敏性肺炎与特发性肺纤维化——病例报告]

[Hypersensitivity pneumonitis and idiopathic pulmonary fibrosis - case report].

作者信息

Mackiewicz Barbara, Siwiec Jan, Czekajska-Chehab Elżbieta, Milanowski Janusz

机构信息

Medical University of Lublin, Poland: Chair and Department of Pneumonology, Oncology and Allergology.

Medical University of Lublin, Poland: I Department of Medical Radiology.

出版信息

Pol Merkur Lekarski. 2018 Mar 27;44(261):152-156.

Abstract

Hypersensitivity pneumonitis (HP), called extrinsic allergic alveolitis, is a syndrome characterized by diffuse inflammation of lung parenchyma and airways in response to the inhalation of antigens to witch the patient has been previously sensitized. The clinical presentation of HP have been categorized as acute, subacute and chronic. The patient with chronic HP may lack a history of acute episodes and usually reports the insidious onset of cough, dyspnoea, fatigue, and weight los. Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring (fibrosis) of the lungs for an unknown reason. Symptoms of IPF are the same as in chronic hypersensitivity pneumonitis and differentiation may be difficult. We present a case of patient with chronic HP, in whom the course of the end stage of the disease mimic acute exacerbations idiopathic pulmonary fibrosis.

摘要

过敏性肺炎(HP),又称外源性过敏性肺泡炎,是一种综合征,其特征为肺实质和气道因吸入患者先前已致敏的抗原而发生弥漫性炎症。HP的临床表现分为急性、亚急性和慢性。慢性HP患者可能没有急性发作史,通常表现为隐匿起病的咳嗽、呼吸困难、疲劳和体重减轻。特发性肺纤维化(IPF)是一种肺部疾病,病因不明,可导致肺部瘢痕形成(纤维化)。IPF的症状与慢性过敏性肺炎相同,鉴别可能困难。我们报告一例慢性HP患者,其疾病终末期病程类似特发性肺纤维化急性加重。

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