Urueña-Palacio Stefania, Ferreyro Bruno L, Fernández-Otero Lucas G, Calo Pablo D
Department of Internal Medicine, Hospital Italiano de Buenos Aires, Autonomous City of Buenos Aires, Argentina.
Department of Internal Medicine, Hospital Italiano de San Justo Agustín Rocca, San Justo, Buenos Aires, Argentina.
BMJ Case Rep. 2018 Mar 30;2018:bcr-2017-223686. doi: 10.1136/bcr-2017-223686.
Scurvy is a nutritional disease caused by ascorbic acid deficiency and is potentially fatal. It was originally described in the 18th century by James Lind and associated with long sea voyages and insufficient citrus consumption. Its prevalence has declined markedly over the years but has still been described sporadically in certain countries. A 22-year-old woman with an anxiety disorder and anorexia nervosa, recent pregnancy and ongoing breast feeding, presented with a 10-day history of spontaneous haematomas in the lower limbs, gingivorrhagia and fatigue. The examination was remarkable for signs of minor bleeding without haemodynamic compromise, gonalgia and pale skin. Work-up studies revealed the presence of anaemia. Direct anamnesis identified a diet based solely of tea and carbohydrates due to distorted body image. With the working diagnosis of scurvy, nutritional support and oral vitamin C supplementation was initiated. Her symptoms and anaemia resolved in 30 days and the diagnosis was confirmed biochemically.
坏血病是一种由抗坏血酸缺乏引起的营养性疾病,有潜在致命风险。它最初在18世纪由詹姆斯·林德描述,与长期海上航行和柑橘类水果摄入不足有关。多年来其发病率已显著下降,但在某些国家仍有散发病例报道。一名22岁患有焦虑症和神经性厌食症、近期怀孕且正在哺乳的女性,出现下肢自发性血肿、牙龈出血和疲劳10天的症状。检查发现有轻微出血迹象但无血流动力学障碍、关节痛和皮肤苍白。检查研究显示存在贫血。直接问诊发现由于身体形象扭曲,其饮食仅为茶和碳水化合物。根据坏血病的初步诊断,开始给予营养支持和口服维生素C补充剂。她的症状和贫血在30天内得到缓解,生化检查确诊了诊断。