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成人脊柱畸形治疗的决策因素。

Decision-making factors in the treatment of adult spinal deformity.

机构信息

L'Institut de la Colonne Vertébrale, Bordeaux University Hospital, Place Amélie Raba-Léon, 33076, Bordeaux, France.

Department of Orthopedic Surgery, Osaka Medical College, Osaka, Japan.

出版信息

Eur Spine J. 2018 Sep;27(9):2312-2321. doi: 10.1007/s00586-018-5572-6. Epub 2018 Mar 30.

Abstract

PURPOSE

We aimed to elucidate the factors for the decision-making process in the treatment of adult spinal deformity (ASD), including sagittal parameters, that impact health-related quality of life (HRQOL).

METHODS

A multicenter prospective ASD database was retrospectively reviewed. The demographic data, HRQOL, and radiographic measures were analyzed using multivariate analyses in younger (≤ 50 years) and older (> 50 years) age groups.

RESULTS

This study included 414 patients (134 surgical and 280 nonsurgical; mean age 30.7 years) in the younger age group and 575 patients (323 surgical and 252 nonsurgical; mean age 65.8 years) in the older age group. Worse HRQOL measures drove surgical treatment, both in younger and older patients. The SRS-22 self-image score was the most differentiating domain, both in the younger and older age groups, and an additional significant factor in the older age group was pain and disability. Coronal deformity drove surgical treatment for the younger age group; however, older surgical patients were less likely to have coronal malalignment. Sagittal parameters were associated with the decision-making process. Greater pelvic incidence minus lumbar lordosis mismatch in the younger age group and smaller lumbar lordosis index in the older age group were most correlated with the decision to undergo surgery.

CONCLUSIONS

Aside from the HRQOL measures and coronal deformity, sagittal parameters were identified as significant factors for the decision-making process in the ASD population, and the lack of lumbar lordosis in relation to pelvic incidence was a strong driver to pursue surgical treatment. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

我们旨在阐明治疗成人脊柱畸形(ASD)时决策过程的相关因素,包括矢状参数,这些因素会影响与健康相关的生活质量(HRQOL)。

方法

回顾性分析多中心前瞻性 ASD 数据库。在年轻(≤50 岁)和老年(>50 岁)年龄组中,使用多元分析对人口统计学数据、HRQOL 和影像学测量值进行分析。

结果

本研究包括年轻年龄组的 414 例患者(134 例手术和 280 例非手术;平均年龄 30.7 岁)和老年年龄组的 575 例患者(323 例手术和 252 例非手术;平均年龄 65.8 岁)。在年轻和老年患者中,较差的 HRQOL 测量值是推动手术治疗的主要因素。SRS-22 自我形象评分是区分两组的最显著指标,在老年患者中,疼痛和残疾是另一个重要因素。冠状畸形是年轻患者选择手术治疗的主要因素;然而,老年手术患者的冠状面不匹配程度较低。矢状参数与决策过程相关。年轻年龄组中骨盆入射角与腰椎前凸差值较大,老年年龄组中腰椎前凸指数较小与手术决策的相关性最强。

结论

除 HRQOL 测量值和冠状畸形外,矢状参数也被确定为 ASD 人群决策过程的重要因素,与骨盆入射角相比腰椎前凸的缺失是进行手术治疗的主要驱动力。这些幻灯片可以在电子补充材料中检索到。

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