在动脉粥样硬化性狭窄基础上合并痉挛的患者中行经皮腔内冠状动脉成形术。
Percutaneous transluminal coronary angioplasty in patients with spasm superimposed on atherosclerotic narrowing.
作者信息
Bertrand M E, Lablanche J M, Fourrier J L, Traisnel G
机构信息
Division of Cardiology, University Hospital of Lille, France.
出版信息
Br Heart J. 1987 Nov;58(5):469-72. doi: 10.1136/hrt.58.5.469.
Of 552 patients undergoing percutaneous transluminal coronary angioplasty 102 had coronary artery spasm superimposed on atherosclerotic narrowing. Coronary angioplasty was successful in 97 (95%). The patients were discharged on a regimen of nifedipine (40-60 mg/day). Seventy six patients were symptom free 6-8 months after the procedure. Restenosis was detected in 35% of patients. Coronary artery spasm was provoked in 38 (44%) of the 87 patients who underwent an ergometrine maleate test. Twenty seven of the 34 patients with restenosis had a provocation test and coronary artery spasm was superimposed on restenosis in 22 (81.5%). Coronary angioplasty is feasible in patients with coronary artery spasm superimposed on atherosclerotic narrowing but the rate of restenosis is high and coronary artery spasm could have a role in the pathogenesis of restenosis.
在552例行经皮腔内冠状动脉成形术的患者中，102例在动脉粥样硬化性狭窄基础上合并冠状动脉痉挛。冠状动脉成形术成功97例（95%）。患者出院时服用硝苯地平（40 - 60毫克/天）。76例患者术后6 - 8个月无症状。35%的患者检测到再狭窄。在87例行马来酸麦角新碱试验的患者中，38例（44%）诱发冠状动脉痉挛。34例再狭窄患者中的27例进行了激发试验，22例（81.5%）再狭窄患者合并冠状动脉痉挛。冠状动脉成形术对于合并动脉粥样硬化性狭窄的冠状动脉痉挛患者是可行的，但再狭窄率较高，且冠状动脉痉挛可能在再狭窄的发病机制中起作用。
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