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Dopamine D2 receptors increase in the dorsolateral striatum of weaver mutant mice.

作者信息

Kaseda Y, Ghetti B, Low W C, Richter J A, Simon J R

机构信息

Department of Physiology and Biophysics, Indiana University School of Medicine, Indianapolis 46223.

出版信息

Brain Res. 1987 Sep 29;422(1):178-81. doi: 10.1016/0006-8993(87)90555-5.

DOI:10.1016/0006-8993(87)90555-5
PMID:2960423
Abstract

Dopamine D2 receptors were studied in homozygous weaver mutant mice (wv/wv), heterozygous littermates (wv/+), and normal mice (+/+). Specific [3H]spiperone binding was significantly higher in the dorsolateral part of the striatum in the weaver mutant mice (wv/wv) than in normal mice (+/+). No significant differences among the 3 genotypes were found in other parts of the striatum or in the nucleus accumbens.

摘要

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引用本文的文献

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Endogenous serotonin release from the dopamine-deficient striatum of the weaver mutant mouse.源自韦弗突变小鼠多巴胺缺乏纹状体的内源性5-羟色胺释放。
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