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股腘动脉闭塞的局部溶栓治疗:早期和晚期结果

Local thrombolysis in femoropopliteal occlusion: early and late results.

作者信息

Wilms G E, Verhaeghe R H, Pouillon M M, Dewaele D, Baert A L, Vermylen J, Verstraete M

机构信息

Department of Radiology, University of Leuven, Belgium.

出版信息

Cardiovasc Intervent Radiol. 1987;10(5):272-5. doi: 10.1007/BF02578008.

DOI:10.1007/BF02578008
PMID:2960451
Abstract

The early and late results of local thrombolysis with low-dose streptokinase followed by balloon dilatation in 64 patients with an occluded femoropopliteal artery are reviewed. The primary success rate was 77% for the native arteries; it was higher (80%) for short (less than 10 cm) as compared with long occlusion (40%) and for patients with claudication as compared with those with advanced ischemia (89% versus 48%). Eleven complications were observed in 10 patients, most frequently a local hematoma at the puncture site. Ascending thrombosis and absence of lysis or incomplete lysis were the main reasons for failure. The cumulative patency rate after 1 and 2 years follow-up was 87% and 82%, respectively.

摘要

回顾了64例股腘动脉闭塞患者采用低剂量链激酶局部溶栓后行球囊扩张术的早期和晚期结果。原生动脉的主要成功率为77%;与长段闭塞(40%)相比,短段闭塞(小于10 cm)的成功率更高(80%),与重度缺血患者相比,间歇性跛行患者的成功率更高(89%对48%)。10例患者出现11种并发症,最常见的是穿刺部位局部血肿。上行性血栓形成以及未溶栓或溶栓不完全是失败的主要原因。随访1年和2年后的累积通畅率分别为87%和82%。

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引用本文的文献

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本文引用的文献

1
Local low-dose thrombolytic therapy of peripheral arterial occlusions.外周动脉闭塞的局部低剂量溶栓治疗。
N Engl J Med. 1982 Dec 23;307(26):1627-30. doi: 10.1056/NEJM198212233072606.
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Low-dose fibrinolytic therapy. Results and new concepts.小剂量纤维蛋白溶解疗法。结果与新概念。
Radiology. 1983 Sep;148(3):663-70. doi: 10.1148/radiology.148.3.6878681.
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Low-dose streptokinase for selective thrombolysis: systemic effects and complications.低剂量链激酶用于选择性溶栓:全身效应及并发症
Radiology. 1984 Jul;152(1):35-9. doi: 10.1148/radiology.152.1.6729135.
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Percutaneous embolectomy by transcatheter aspiration. Work in progress.经导管抽吸进行经皮取栓术。正在进行中。
Radiology. 1984 Feb;150(2):357-61. doi: 10.1148/radiology.150.2.6228952.
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The effect of streptokinase infusion on chronic arterial occlusions and stenoses.链激酶输注对慢性动脉闭塞和狭窄的影响。
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Outcome of recent thromboembolic occlusions of limb arteries treated with streptokinase.近期采用链激酶治疗的肢体动脉血栓栓塞性闭塞的结果
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Selective clot lysis with low-dose streptokinase.低剂量链激酶的选择性血栓溶解
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Fibrinolysis in chronic arteriosclerotic occlusions: intrathrombotic injections of streptokinase. Work in progress.慢性动脉硬化闭塞症中的纤维蛋白溶解:链激酶的血栓内注射。研究进展。
Radiology. 1985 Oct;157(1):45-50. doi: 10.1148/radiology.157.1.4034976.
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Local thrombolysis in the treatment of thrombosed arteries, bypass grafts, and arteriovenous fistulas.局部溶栓治疗血栓形成的动脉、旁路移植物和动静脉瘘。
J Vasc Surg. 1985 May;2(3):406-14. doi: 10.1067/mva.1985.avs0020406.
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Suggested standards for reports dealing with lower extremity ischemia. Prepared by the Ad Hoc Committee on Reporting Standards, Society for Vascular Surgery/North American Chapter, International Society for Cardiovascular Surgery.下肢缺血相关报告的建议标准。由血管外科学会/北美分会、国际心血管外科学会报告标准特设委员会编写。
J Vasc Surg. 1986 Jul;4(1):80-94.