Reyes Lee Marvin, Aguilar Juan León, Villamor Perla, De La Torre Carlos, Álvarez Alicia, Mantilla Edgar, Álvarez-Neri Hiram
Department of Pediatric Otolaryngology, Hospital Infantil de México, Federico Gómez, Mexico.
Department of Pediatric Otolaryngology, Hospital Infantil de México, Federico Gómez, Mexico.
Int J Pediatr Otorhinolaryngol. 2018 May;108:63-66. doi: 10.1016/j.ijporl.2018.02.025. Epub 2018 Feb 17.
Juvenile recurrent respiratory papillomatosis (JRRP) is generally aggressive and with a high recurrence rate. Currently, there is no definite curative treatment for JRRP. Therefore, a greater understanding of the aspects that influence the severity and prognosis of the disease is required.
The aim of this study was to establish the clinical and socioeconomic characteristics of pediatric patients with JRRP and its relationship with the severity of the disease in a tertiary care pediatric hospital.
A strong relationship was observed between the severity of the disease and the age at the time of diagnosis, and having a tracheostomy. A moderate association was found between the severity of the disease and the age at the time of the study, the area of origin and the recurrence rate. None of the socioeconomic statuses had a correlation with the severity of the JRRP.
JRRP is associated with multiple surgeries due to the recurrence and aggressiveness of the disease. The socioeconomic status does not seem to influence the severity of the disease, whereas younger patients and users of tracheostomy should receive a more strict follow-up given the increased risk of severe disease.
青少年复发性呼吸道乳头状瘤病（JRRP）通常具有侵袭性且复发率高。目前，尚无针对JRRP的确切治愈性治疗方法。因此，需要更深入了解影响该疾病严重程度和预后的因素。
本研究的目的是确定一家三级儿科医院中JRRP患儿的临床和社会经济特征及其与疾病严重程度的关系。
观察到疾病严重程度与诊断时的年龄以及是否进行气管切开术之间存在密切关系。发现疾病严重程度与研究时的年龄、起源部位和复发率之间存在中度关联。社会经济状况均与JRRP的严重程度无相关性。
由于疾病的复发和侵袭性，JRRP与多次手术相关。社会经济状况似乎不影响疾病的严重程度，而鉴于严重疾病风险增加，年轻患者和气管切开术使用者应接受更严格的随访。
