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头动征在研究中影响敏感性和特异性的因素。

Factors affecting sensitivity and specificity of head-turning sign in the studies.

机构信息

Kayseri Education and Research Hospital,Geriatric Center,Kayseri,Turkey.

Unit for Aging Brain and Dementia,Department of Geriatric Medicine,Faculty of Medicine,Dokuz Eylul University,Izmir,Turkey.

出版信息

Int Psychogeriatr. 2018 Oct;30(10):1571-1572. doi: 10.1017/S1041610218000133. Epub 2018 Apr 2.

Abstract

We read with interest the comment by Williamson and Larner on our recent study titled "Attended With and Head-Turning Sign can be clinical markers of cognitive impairment in older adults" (Soysal et al., 2017). After the authors read the study, they re-examined their data according to the presence of Attended With (AW) and Head-Turning Sign (HTS), and compared their results with ours (Larner, 2014). Then, they found that while the sensitivity, specificity, positive predictive value, and negative predictive value of AW in detecting cognitive impairment were similar to ours, HTS had lower sensitivity (80.95% vs. 65.0%) and higher specificity (64.7% vs. 95.0%) than our results (Larner, 2014; Soysal et al., 2017). We think that some methodological and cultural differences may explain these discrepancies between the two.

摘要

我们饶有兴趣地阅读了 Williamson 和 Larner 对我们最近题为“Attended With 和 Head-Turning Sign 可作为老年人认知障碍的临床标志物”的研究的评论(Soysal 等人,2017 年)。作者阅读了这项研究后,根据 Attended With (AW) 和 Head-Turning Sign (HTS) 的存在重新检查了他们的数据,并将他们的结果与我们的结果进行了比较(Larner,2014 年)。然后,他们发现,虽然 AW 在检测认知障碍方面的敏感性、特异性、阳性预测值和阴性预测值与我们的相似,但 HTS 的敏感性(80.95%对 65.0%)低于我们的结果,特异性(64.7%对 95.0%)高于我们的结果(Larner,2014 年;Soysal 等人,2017 年)。我们认为,一些方法学和文化差异可能解释了这两项研究之间的这些差异。

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