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[转头征作为痴呆诊断的标志物]

[Head turn sign as a marker of dementia diagnosis].

作者信息

O Neill Santiago, Richly Pablo, Pontello Noelia, Christie Corina, Flores Ignacio, Dorman Guido, Rojas Galeno

机构信息

Instituto de Neurociencias del Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina. INCYT-CONICET.

出版信息

Vertex. 2019 Jan-Feb;XXX(143):18-21.

PMID:31968026
Abstract

Due to the phenomenon of ageing population, cognitive impairment has become more prevalent, and any marker able to improve its detection becomes of significant importance. With that objective in mind, a prospective observational study was performed in a medical consultation related to cognitive impairment. 150 subjects (58% women) were included with an average age of 76 years (SD 8.6). The Head Turn sign was positive for 32 subjects with a sensitivity of 41.7% for dementia, a specificity of 93.7% and a negative predictive value of 64.4%. This study shows the semiologic value of a simple clinical sign, easy to spot in the daily practice and most helpful to alert physicians about a likely dementia diagnosis.

摘要

由于人口老龄化现象,认知障碍变得更加普遍,任何能够改善其检测的标志物都变得至关重要。出于这一目的,在一次与认知障碍相关的医疗咨询中进行了一项前瞻性观察研究。纳入了150名受试者(58%为女性),平均年龄为76岁(标准差8.6)。32名受试者的头部转动征呈阳性,对痴呆的敏感性为41.7%,特异性为93.7%,阴性预测值为64.4%。这项研究显示了一个简单临床体征的症状学价值,该体征在日常实践中易于发现,对提醒医生注意可能的痴呆诊断非常有帮助。

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