消毒剂对牙科设备水线的去污效果：一项实验室研究。
The efficacy of disinfectants in the decontamination of dental unit water lines: an laboratory study.
作者信息
Patel Mrudula, Desai Jainisha, Owen Peter C
机构信息
Division of Oral Microbiology, Department of Oral Biological Sciences, School of Oral Health Sciences, Faculty of Health Sciences, University of The Witwatersrand, Johannesburg, South Africa.
Department of Oral Rehabilitation, School of Oral Health Sciences, Faculty of Health Sciences, University of The Witwatersrand, Johannesburg, South Africa.
出版信息
BDJ Open. 2016 Feb 26;2:16003. doi: 10.1038/bdjopen.2016.3. eCollection 2016.
OBJECTIVES/AIMS: This laboratory study compared the efficacy of water, sodium percarbonate (SPC) and chlorine dioxide (ClO) solutions in the disinfection of dental unit water lines (DUWLs).
MATERIALS AND METHODS
New DUWL tubes were cut, split open, and mono-culture and mixed-culture biofilms of , and were grown. Harvested biofilms from the sectioned DUWL tubes were exposed to sterile distilled water, SPC or 5 and 10 p.p.m. ClO in both a stationary phase and through a constant flow. Bacterial counts were compared using the Kruskal-Wallis nonparametric rank test.
RESULTS
In the mono-culture biofilms, SPC, 5 and 10 p.p.m. ClO significantly reduced all the test organisms (<0.01). However, no significant difference was found between SPC and ClO. In the mixed-culture biofilms exposed to disinfectant without flow, ClO significantly reduced the biofilm (=0.02) compared with water and SPC. Similarly, in the constant flow study, ClO proved to be superior to water.
CONCLUSION
At low concentrations, ClO with and without flow significantly reduced the mixed-culture biofilm grown on the sections of the DUWL tubes. Therefore, it has the potential to be used in the patient treatment water, as it is potable at these concentrations, and to decontaminate and limit the biofilm formation in the water lines.
目的
本实验室研究比较了水、过碳酸钠（SPC）和二氧化氯（ClO）溶液对牙科设备水线（DUWLs）的消毒效果。
材料与方法
将新的DUWL管切割、劈开，培养形成、和的单培养和混合培养生物膜。将从切开的DUWL管中收获的生物膜分别置于无菌蒸馏水中，以及5和10 ppm的SPC或ClO中，分别处于静止状态和持续流动状态。使用Kruskal-Wallis非参数秩和检验比较细菌计数。
结果
在单培养生物膜中，SPC、5和10 ppm的ClO均能显著减少所有受试微生物（<0.01）。然而，SPC和ClO之间未发现显著差异。在无流动的情况下暴露于消毒剂的混合培养生物膜中，与水和SPC相比，ClO能显著减少生物膜（=0.02）。同样，在持续流动研究中，ClO被证明优于水。
结论
在低浓度下，无论有无流动，ClO均能显著减少DUWL管段上生长的混合培养生物膜。因此，它有潜力用于患者治疗用水，因为在这些浓度下它是可饮用的，并且能够对水线进行去污并限制生物膜形成。
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