伴有腹膜受累和腹水的卵巢结节病中CA 15-3水平假性升高

Tsiodras Sotirios, Gouloumi Alina-Roxani, Tsakiraki Zoi, Chrelias George, Chrelias Charalambos, Loukides Stylianos, Panayiotides Ioannis

4th Department of Internal Medicine, University of Athens Medical School, "Attikon" University Hospital, Athens, Greece.

2nd Department of Pathology, University of Athens Medical School, "Attikon" University Hospital, Athens, Greece.

Case Rep Obstet Gynecol. 2018 Jan 22;2018:2039730. doi: 10.1155/2018/2039730. eCollection 2018.

A rare case of ovarian sarcoidosis with peritoneal and omental involvement presenting as an ovarian malignancy is presented. Clinical, laboratory, and radiological evaluation of the patient revealed ascites and high levels of serum CA 125 and CA 15.3. The diagnosis of sarcoidosis was confirmed with pathology findings on tissues obtained during surgical laparotomy. Establishing the diagnosis of sarcoidosis can be treacherous and was complicated in this case by the falsely elevated biomarkers and ascites.

本文报告一例罕见的卵巢结节病，伴有腹膜和大网膜受累，表现为卵巢恶性肿瘤。对该患者进行的临床、实验室和影像学评估显示有腹水，血清CA 125和CA 15.3水平升高。通过手术剖腹探查获取的组织病理结果确诊为结节病。结节病的诊断可能具有挑战性，在本例中，生物标志物假性升高和腹水使诊断变得复杂。