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有精神和物质使用障碍与无精神和物质使用障碍者的戒烟治疗结局:一项观察性真实世界研究。

Smoking cessation treatment outcomes among people with and without mental and substance use disorders: An observational real-world study.

机构信息

Department of Neuroscience, Medical School, ABC Foundation, André Santo, SP, Brazil; Clima Clinic, São Paulo, SP, Brazil; ABC Center for Mental Health Studies, Santo André, SP, Brazil; Department of Psychiatry, Medical School, University of São Paulo, São Paulo, SP, Brazil.

Department of Neuroscience, Medical School, ABC Foundation, André Santo, SP, Brazil.

出版信息

Eur Psychiatry. 2018 Aug;52:22-28. doi: 10.1016/j.eurpsy.2018.02.005. Epub 2018 Mar 30.

Abstract

BACKGROUND

There is a lack of studies evaluating smoking cessation treatment protocols which include people with and without mental and substance use disorders (MSUD), and which allows for individuals with MSUD undergoing their psychiatric treatment.

METHODS

We compared treatment success between participants with (n = 277) and without (n = 419) MSUD among patients in a 6-week treatment provided by a Brazilian Psychosocial Care Center (CAPS) from 2007 to 2013. Sociodemographic, medical and tobacco use characteristics were assessed at baseline. Tobacco treatment consisted of 1) group cognitive behavior therapy, which included people with and without MSUD in the same groups, and 2) pharmacotherapy, which could include either nicotine patches, nicotine gum, bupropion or nortriptyline. For participants with MSUD, tobacco treatment was integrated into their ongoing mental health treatment. The main outcome was 30-day point prevalence abstinence, measured at last day of treatment.

RESULTS

Abstinence rates did not differ significantly between participants with and without MSUD (31.1% and 34.4%, respectively). Variables that were significantly associated with treatment success included years smoking, the Heaviness of Smoking Index, and use of nicotine patch or bupropion.

CONCLUSION

The inclusion of individuals with and without MSUD in the same protocol, allowing for individuals with MSUD undergoing their psychiatric treatment, generates at least comparable success rates between the groups. Predictors of treatment success were similar to those found in the general population. Facilities that treat patients with MSUD should treat tobacco use in order to reduce the disparities in morbidity and mortality experienced by this population.

摘要

背景

缺乏评估包括有和无精神和物质使用障碍(MSUD)患者的戒烟治疗方案的研究,并且这些方案允许 MSUD 患者在接受精神科治疗的同时接受治疗。

方法

我们比较了 2007 年至 2013 年期间,一家巴西心理社会护理中心(CAPS)提供的为期 6 周的治疗中,有(n=277)和无(n=419)MSUD 患者的治疗成功率。在基线时评估了人口统计学、医学和烟草使用特征。烟草治疗包括 1)团体认知行为疗法,其中包括有和无 MSUD 的患者在同一组中,以及 2)药物治疗,其中可能包括尼古丁贴片、尼古丁口香糖、安非他酮或去甲替林。对于有 MSUD 的参与者,烟草治疗被整合到他们正在进行的心理健康治疗中。主要结局是治疗结束时的 30 天点患病率戒断,即最后一天的测量结果。

结果

有和无 MSUD 的参与者的戒断率没有显著差异(分别为 31.1%和 34.4%)。与治疗成功显著相关的变量包括吸烟年限、吸烟严重程度指数和使用尼古丁贴片或安非他酮。

结论

将有和无 MSUD 的个体纳入同一方案中,允许 MSUD 患者在接受精神科治疗的同时接受治疗,至少可以在两组之间产生相当的成功率。治疗成功的预测因素与一般人群相似。治疗 MSUD 患者的机构应该治疗烟草使用,以减少该人群所经历的发病率和死亡率的差异。

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