青少年时期吸烟作为影响成年后吸烟治疗的一个因素的试验。一项回顾性队列研究。
Experimentation with tobacco during adolescence as a factor influencing treatment of smoking in adulthood. A retrospective cohort.
作者信息
Chaim Carolina Hanna, Siu Erica Rosanna, Carvalho Carlos Felipe Cavalcanti, Frallonardo Fernanda Piotto, Ismael Flavia, Andrade Arthur Guerra de, Ventriglio Antonio, Torales Julio, Bhugra Dinesh, Castaldelli-Maia João Mauricio
机构信息
MD. Research Associate, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.
PhD. Research Associate, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.
出版信息
Sao Paulo Med J. 2019 Jul 29;137(3):234-240. doi: 10.1590/1516-3180.2018.0504140319.
BACKGROUND
There are still few studies on predictors of smoking cessation in Brazilian samples. Experimentation with tobacco during adolescence (ETA) may be one of the important predictors.
OBJECTIVE
This study aimed, within the context of a treatment-seeking group of subjects, to test the hypothesis that ETA negatively affects the outcome of smoking cessation during adulthood.
DESIGN AND SETTING
Retrospective (historic) cohort study conducted at a psychosocial care center in São Paulo, Brazil, between 2007 and 2010.
METHODS
Data on sociodemographics, smoking and medical profiles were obtained through self-report questionnaires that were completed at the baseline and at any follow-up appointment. Logistic regression models were constructed to describe factors associated with the outcome of smoking cessation, measured according to the self-reported four-week success rate among 367 outpatient smokers.
RESULTS
ETA was found to be associated with not quitting smoking through the treatment (odds ratio = 0.57; 95% confidence interval = 0.33-0.96; P < 0.05), even after adjustment for dependence level, sociodemographics, nicotine patch use and number of years of smoking.
CONCLUSIONS
Early exposure to nicotine may lead to higher risk of continuing smoking after treatment, in adulthood.
背景
针对巴西样本中戒烟预测因素的研究仍然较少。青少年时期尝试吸烟（ETA）可能是重要的预测因素之一。
目的
在寻求治疗的受试者群体背景下，本研究旨在检验ETA对成年期戒烟结果产生负面影响这一假设。
设计与地点
2007年至2010年期间，在巴西圣保罗的一家社会心理护理中心开展的回顾性（历史性）队列研究。
方法
通过在基线和任何随访预约时完成的自我报告问卷，获取社会人口统计学、吸烟和医疗状况的数据。构建逻辑回归模型，以描述与戒烟结果相关的因素，戒烟结果根据367名门诊吸烟者自我报告的四周成功率来衡量。
结果
即使在对依赖程度、社会人口统计学、尼古丁贴片使用情况和吸烟年限进行调整之后，仍发现ETA与治疗后未戒烟相关（比值比=0.57；95%置信区间=0.33-0.96；P<0.05）。
结论
成年期早期接触尼古丁可能导致治疗后继续吸烟的风险更高。
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