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本文引用的文献

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The effectiveness of Cytisine versus Nicotine Replacement Treatment for smoking cessation in the Russian Federation.在俄罗斯联邦，金雀花碱与尼古丁替代疗法对戒烟的有效性比较。
Int J Drug Policy. 2018 Aug;58:121-125. doi: 10.1016/j.drugpo.2018.05.012. Epub 2018 Jun 18.
2
Investigating the dimensional diagnosis of ICD-11 nicotine dependence.探讨 ICD-11 尼古丁依赖的维度诊断。
Psychol Addict Behav. 2018 Jun;32(4):415-425. doi: 10.1037/adb0000369.
3
Smoking cessation treatment outcomes among people with and without mental and substance use disorders: An observational real-world study.有精神和物质使用障碍与无精神和物质使用障碍者的戒烟治疗结局：一项观察性真实世界研究。
Eur Psychiatry. 2018 Aug;52:22-28. doi: 10.1016/j.eurpsy.2018.02.005. Epub 2018 Mar 30.
4
The latent trait of ICD-11 nicotine dependence criteria: Dimensional and categorical phenotypes.ICD-11 尼古丁依赖标准的潜在特征：维度和分类表型。
Psychiatry Res. 2018 Aug;266:275-283. doi: 10.1016/j.psychres.2018.03.018. Epub 2018 Mar 19.
5
Early onset cigarette smokers exhibit greater P300 reactivity to smoking-related stimuli and report greater craving.早发型吸烟者对与吸烟相关的刺激表现出更大的P300反应性，并报告有更强烈的渴望。
Brain Res. 2018 May 15;1687:173-184. doi: 10.1016/j.brainres.2018.02.037. Epub 2018 Mar 7.
6
Predictors of smoking cessation: A longitudinal study in a large cohort of smokers.戒烟预测因素：一项大型吸烟者队列的纵向研究。
Respir Med. 2017 Nov;132:164-169. doi: 10.1016/j.rmed.2017.10.013. Epub 2017 Oct 19.
7
Smoking Cessation Treatment for Patients With Mental Disorders Using CBT and Combined Pharmacotherapy.使用认知行为疗法和联合药物疗法对精神障碍患者进行戒烟治疗。
J Dual Diagn. 2017 Oct-Dec;13(4):238-246. doi: 10.1080/15504263.2017.1328149. Epub 2017 May 10.
8
Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial.在有和没有精神疾病的吸烟者中，评估伐伦克林、安非他酮和尼古丁贴片的神经精神安全性和疗效（EAGLES）：一项双盲、随机、安慰剂对照临床试验。
Lancet. 2016 Jun 18;387(10037):2507-20. doi: 10.1016/S0140-6736(16)30272-0. Epub 2016 Apr 22.
9
Factors associated with smoking cessation.与戒烟相关的因素。
Rev Saude Publica. 2015;49:10. doi: 10.1590/s0034-8910.2015049004946. Epub 2015 Feb 27.
10
Retention predictors of a smoking treatment provided by a public psychosocial unit in Brazil.巴西一个公共社会心理机构提供的吸烟治疗的留存预测因素。
Int Rev Psychiatry. 2014 Aug;26(4):515-23. doi: 10.3109/09540261.2014.928272.

青少年时期吸烟作为影响成年后吸烟治疗的一个因素的试验。一项回顾性队列研究。

Experimentation with tobacco during adolescence as a factor influencing treatment of smoking in adulthood. A retrospective cohort.

作者信息

Chaim Carolina Hanna, Siu Erica Rosanna, Carvalho Carlos Felipe Cavalcanti, Frallonardo Fernanda Piotto, Ismael Flavia, Andrade Arthur Guerra de, Ventriglio Antonio, Torales Julio, Bhugra Dinesh, Castaldelli-Maia João Mauricio

机构信息

MD. Research Associate, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.

PhD. Research Associate, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.

出版信息

Sao Paulo Med J. 2019 Jul 29;137(3):234-240. doi: 10.1590/1516-3180.2018.0504140319.

DOI:10.1590/1516-3180.2018.0504140319
PMID:31365599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9743999/
Abstract

BACKGROUND

There are still few studies on predictors of smoking cessation in Brazilian samples. Experimentation with tobacco during adolescence (ETA) may be one of the important predictors.

OBJECTIVE

This study aimed, within the context of a treatment-seeking group of subjects, to test the hypothesis that ETA negatively affects the outcome of smoking cessation during adulthood.

DESIGN AND SETTING

Retrospective (historic) cohort study conducted at a psychosocial care center in São Paulo, Brazil, between 2007 and 2010.

METHODS

Data on sociodemographics, smoking and medical profiles were obtained through self-report questionnaires that were completed at the baseline and at any follow-up appointment. Logistic regression models were constructed to describe factors associated with the outcome of smoking cessation, measured according to the self-reported four-week success rate among 367 outpatient smokers.

RESULTS

ETA was found to be associated with not quitting smoking through the treatment (odds ratio = 0.57; 95% confidence interval = 0.33-0.96; P < 0.05), even after adjustment for dependence level, sociodemographics, nicotine patch use and number of years of smoking.

CONCLUSIONS

Early exposure to nicotine may lead to higher risk of continuing smoking after treatment, in adulthood.

摘要

背景

针对巴西样本中戒烟预测因素的研究仍然较少。青少年时期尝试吸烟（ETA）可能是重要的预测因素之一。

目的

在寻求治疗的受试者群体背景下，本研究旨在检验ETA对成年期戒烟结果产生负面影响这一假设。

设计与地点

2007年至2010年期间，在巴西圣保罗的一家社会心理护理中心开展的回顾性（历史性）队列研究。

方法

通过在基线和任何随访预约时完成的自我报告问卷，获取社会人口统计学、吸烟和医疗状况的数据。构建逻辑回归模型，以描述与戒烟结果相关的因素，戒烟结果根据367名门诊吸烟者自我报告的四周成功率来衡量。

结果

即使在对依赖程度、社会人口统计学、尼古丁贴片使用情况和吸烟年限进行调整之后，仍发现ETA与治疗后未戒烟相关（比值比=0.57；95%置信区间=0.33-0.96；P<0.05）。

结论

成年期早期接触尼古丁可能导致治疗后继续吸烟的风险更高。