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[育龄妇女妊娠间隔对单活产新生儿出生体重的影响]

[Effect of interpregnancy interval of childbearing aged women on birth weight of single live birth neonates].

作者信息

Zhang Q, Wang L L, Bai R H, Dang S N, Yan H

机构信息

Department of Epidemiology and Health Statistics, School of Public Health, Health Science Center of Xi'an Jiaotong University, Xi'an 710061, China.

Global Health Institute, Health Science Center of Xi'an Jiaotong University, Xi'an 710061, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Mar 10;39(3):317-321. doi: 10.3760/cma.j.issn.0254-6450.2018.03.013.

Abstract

To understand the effect of interpregnancy interval (IPI) of childbearing aged women on the birth weight of single live birth neonates in Shaanxi province. A questionnaire survey was conducted among the childbearing aged women selected through multistage stratified random sampling in Shaanxi during 20l0-2013, all the childbearing aged women had definite pregnancy outcomes. The interpregnancy interval of the childbearing aged women and the birth weight of the newborns were used as the independent variables and dependent variables respectively in multiple linear regression model and quantile regression model, and confounding factors were controlled. A total of 13 063 women at childbearing age and their infants were investigated. The incidence of low birth weight and macrosomia was 3.54% and 7.62% respectively. Multiple linear regression analysis showed that there was no significant difference in birth weight among different IPI group and control group. Quantile regression analysis showed when birth weight was at 5 percentiles, the difference in birth weight between newborns whose mothers had short interpregnancy interval (<12 months) and those in control group was significant, when the birth weight was ≥90 percentiles, the birth weights of newborns whose mothers had long interpregnancy interval (60-119 months) were higher than those in control group, the difference was significant. As the increase of the percentiles of birth weight, the extent of changes gradually increased. The analysis indicated that both short (<12 months) and long (60-119 months) interpregnancy interval would had negative effects on birth weights of newborns. Therefore, planning for pregnancy is important for having a good perinatal outcome.

摘要

为了解陕西省育龄妇女的妊娠间隔(IPI)对单胎活产新生儿出生体重的影响。于2010 - 2013年对陕西省采用多阶段分层随机抽样选取的育龄妇女进行问卷调查,所有育龄妇女均有明确的妊娠结局。将育龄妇女的妊娠间隔和新生儿出生体重分别作为多元线性回归模型和分位数回归模型中的自变量和因变量,并控制混杂因素。共调查了13063名育龄妇女及其婴儿。低出生体重和巨大儿的发生率分别为3.54%和7.62%。多元线性回归分析显示,不同IPI组与对照组的出生体重差异无统计学意义。分位数回归分析显示,当出生体重处于第5百分位数时,母亲妊娠间隔短(<12个月)的新生儿与对照组新生儿的出生体重差异有统计学意义;当出生体重≥第90百分位数时,母亲妊娠间隔长(60 - 119个月)的新生儿出生体重高于对照组,差异有统计学意义。随着出生体重百分位数的增加,变化幅度逐渐增大。分析表明,妊娠间隔短(<12个月)和长(60 - 119个月)均会对新生儿出生体重产生负面影响。因此,计划妊娠对获得良好的围产结局很重要。

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