Sonesson S E, Winberg P, Lundell B P
Department of Pediatrics, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
Pediatr Res. 1987 Oct;22(4):461-4. doi: 10.1203/00006450-198710000-00020.
A range-gated Doppler technique was used to assess intracranial arterial blood flow velocity changes in 20 healthy term infants during the first 3 days after birth. Systolic, diastolic, and mean flow velocity decreased during the first 30 min after birth whereas arterial pressure and heart rate did not change. Mean flow velocity did not change from 30 min to 72 h of life, although systolic and diastolic flow velocity changed in opposite directions. Systolic flow velocity increased to 2 h of age and thereafter decreased. Diastolic flow velocity decreased to a minimum value at 2 h and thereafter increased to 24 h of age. These flow velocity changes suggest an initial decrease in cerebral perfusion, followed by a constant cerebral blood flow during normal circulatory transition after birth.
采用距离选通多普勒技术评估20名足月健康婴儿出生后前3天颅内动脉血流速度的变化。出生后最初30分钟内，收缩期、舒张期和平均血流速度下降，而动脉压和心率未发生变化。出生后30分钟至72小时，平均血流速度未改变，尽管收缩期和舒张期血流速度呈相反方向变化。收缩期血流速度在2小时龄时升高，此后下降。舒张期血流速度在2小时龄时降至最低值，此后在24小时龄时升高。这些血流速度变化表明，出生后正常循环过渡期间，脑灌注最初下降，随后脑血流量保持恒定。
