Kockx Maaike, Kritharides Leonard
Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, Concord Repatriation General Hospital, Gate 3 Hospital Road, Concord, New South Wales 2139, Australia.
Department of Cardiology, Concord Hospital, Atherosclerosis laboratory, ANZAC Research Institute, University of Sydney, 3rd Floor, Hospital Road, Concord, NSW 2139, Australia.
Cardiol Clin. 2018 May;36(2):265-275. doi: 10.1016/j.ccl.2017.12.008.
Plasma triglyceride levels are causally related to an increased risk of cardiovascular disease. Here, the authors summarize their understanding of triglyceride-rich lipoprotein metabolism, previous and newly identified regulators, and their relevance as candidate targets for therapeutic intervention.
血浆甘油三酯水平与心血管疾病风险增加存在因果关系。在此,作者总结了他们对富含甘油三酯脂蛋白代谢、既往及新发现的调节因子,以及这些调节因子作为治疗干预候选靶点的相关性的理解。