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胰腺黏液性囊腺瘤合并急性胰腺炎及腹膜后破裂

[Pancreatic mucinous cystadenoma doubly complicated by acute pancreatitis and retroperitoneal rupture].

作者信息

Maghrebi Houcine, Makni Amine

机构信息

Département de Chirurgie, Hôpital La Rabta, Faculté de Médecine de Tunis, Tunis, Tunisie.

出版信息

Pan Afr Med J. 2017 Nov 6;28:203. doi: 10.11604/pamj.2017.28.203.13715. eCollection 2017.

Abstract

Mucinous cystadenomas are benign tumors with malignant potential. They are often revealed by non-specific abdominal pain, jaundice or an episode of acute pancreatitis. We here report an exceptional case of mucinous cystadenoma doubly complicated by acute pancreatitis and retroperitoneal rupture. The study involved a 30-year old non-weighted female patient, presenting with epigastric pain associated with left hypochondrium evolving over the last three months and which had intensified without fever or jaundice in the last 3 days. Clinical examination showed impingement on palpation of the epigastrium and of the left hypochondrium. There was no palpable mass. Laboratory tests were without abnormalities, except for lipasemia that was 8-times the upper normal. Abdominal CT scan showed bi-loculated cystic mass in the pancreas tail, measuring 111 mm * 73 mm, with a thin wall and a fluid content, associated with an infiltration of the left perirenal fascia. MRI (Panel A) showed mucinous cystadenoma with retroperitoneal rupture. The caudal portion of the main pancreatic duct was slightly dilated and communicated with the pancreatic cyst. The patient underwent surgery via bi-sub-costal approach. A cystic mass in the pancreas tail with retroperitoneal rupture associated with acute pancreatitis (outflow of necrotic content from left anterior prerenal space) was found. Caudal splenopancreatectomy was performed (Panel B). The postoperative course was uneventful. The anatomo-pathological examination of the surgical specimen showed pancreatic mucinous cystadenoma with low-grade dysplasia.

摘要

黏液性囊腺瘤是具有恶性潜能的良性肿瘤。它们常因非特异性腹痛、黄疸或急性胰腺炎发作而被发现。我们在此报告一例黏液性囊腺瘤合并急性胰腺炎和腹膜后破裂的罕见病例。该研究涉及一名30岁未加权的女性患者,患者上腹部疼痛伴左季肋部疼痛,持续了三个月,在过去三天内加重,无发热或黄疸。临床检查显示上腹部和左季肋部触诊时有压痛。未触及肿块。实验室检查无异常,仅脂肪酶血症是正常上限的8倍。腹部CT扫描显示胰腺尾部有一个双房囊性肿块,大小为111毫米×73毫米,壁薄,内含液体,伴有左肾周筋膜浸润。MRI(图A)显示黏液性囊腺瘤伴腹膜后破裂。主胰管尾部轻度扩张并与胰腺囊肿相通。患者通过双侧肋下切口进行手术。发现胰腺尾部有一个囊性肿块伴腹膜后破裂并合并急性胰腺炎(坏死内容物从左肾前间隙流出)。进行了胰尾脾切除术(图B)。术后过程顺利。手术标本的解剖病理学检查显示为胰腺黏液性囊腺瘤伴低级别发育异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf65/5878853/108d7d7b7caf/PAMJ-28-203-g001.jpg

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