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胰腺真性囊肿——诊断与治疗难题

Pancreatic true cysts--diagnosis and treatment difficulties.

作者信息

Vilcea I D, Vasile I, Mirea C, Mesină C, Calota F, Pasalega M, Cheie M, Dumitrescu T, Mogoanta S, Vilcea A-M

机构信息

Second Surgical Clinic, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Chirurgia (Bucur). 2011 May-Jun;106(3):389-94.

PMID:21853751
Abstract

Pancreatic true cysts represent a rare, heterogeneous group of pancreatic tumors; therapeutic strategy is based on patient's general status, cyst topography, and especially the estimated risk of malignancy. This paper aim is to present 7 cases of pancreatic true cysts, operated on a six years period (January 2004-January 2010) in our surgical clinic: 2 men and 5 women, aged between 24-61 years old; cyst diameter varies between 3.5-15 cm, tumor location being pancreatic head in two cases and the distal pancreas in 5 cases. Surgical treatment consisted in cyst enucleation (two cases), splenopancreatectomy (three cases), duodenopancreatectomy (one case), and subtotal splenopancreatectomy (one case). Histology was represented by serous cystadenoma (one case), mucinous cystadenoma (2 cases), intraductal papillary mucinous cystadenoma (one case), and papillary cystadenocarcinoma (3 cases).Postoperative results were good in all cases, with 3 postoperative pancreatic external fistulas, resolved conservatory; no case of post-pancreatectomy diabetes mellitus was registered. In conclusion, surgical removal of the pancreatic cystic tumors is necessary, especially due to the risk of malignancy, at least in the absence of rigorous histological proofs of benignancy. Postoperative results are favorable in terms of postoperative morbidity and mortality.

摘要

胰腺真性囊肿是一组罕见的、异质性的胰腺肿瘤;治疗策略基于患者的一般状况、囊肿的位置,尤其是恶性风险评估。本文旨在介绍我院外科在六年期间(2004年1月至2010年1月)手术治疗的7例胰腺真性囊肿病例:2例男性和5例女性,年龄在24 - 61岁之间;囊肿直径在3.5 - 15厘米之间,肿瘤位于胰头2例,胰体尾5例。手术治疗包括囊肿摘除术(2例)、脾胰切除术(3例)、十二指肠胰切除术(1例)和次全脾胰切除术(1例)。组织学类型包括浆液性囊腺瘤(1例)、黏液性囊腺瘤(2例)、导管内乳头状黏液性囊腺瘤(1例)和乳头状囊腺癌(3例)。所有病例术后结果良好,有3例术后出现胰腺外瘘,经保守治疗治愈;未发生胰切除术后糖尿病病例。总之,胰腺囊性肿瘤的手术切除是必要的,尤其是鉴于存在恶性风险,至少在缺乏严格的良性组织学证据时。就术后发病率和死亡率而言,手术结果是令人满意的。

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