Cancer Discov. 2018 May;8(5):525-526. doi: 10.1158/2159-8290.CD-NB2018-038. Epub 2018 Apr 3.
Researchers have developed a test called PapSEEK that detects endometrial and ovarian cancers by analyzing DNA samples for mutations and aberrations in chromosome number. In a large, retrospective study, the test detected 81% of endometrial cancers and 33% of ovarian cancers with a low false-positive rate.
研究人员开发了一种名为 PapSEEK 的检测方法,通过分析 DNA 样本中染色体数量的突变和异常来检测子宫内膜癌和卵巢癌。在一项大型回顾性研究中,该检测方法对子宫内膜癌的检出率为 81%,对卵巢癌的检出率为 33%,假阳性率较低。