Chang Hsiu-Wen, Kuei Chia-Hao, Tseng Chin-Feng, Hou Yi-Chou, Tseng Ying-Lan
Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, Xin-dian District, New Taipei City, Taiwan, Republic of China.
Division of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan, Republic of China.
Ther Clin Risk Manag. 2018 Mar 23;14:595-599. doi: 10.2147/TCRM.S155978. eCollection 2018.
Urinoma, defined as the urine leakage beyond the urinary tract, is commonly induced by blunt trauma or urinary tract obstruction by stone, intra-abdominal malignancy, or retroperitoneal fibrosis. Spontaneous urinoma is rare and parenchymal pathologic change is rarely mentioned when urinoma is found. We present a case of a 28-year-old woman with bilateral flank pain induced by spontaneous urinoma. The lady received chronic analgesics because of migraine. After intravenous ketorolac injection, bilateral perirenal urinoma developed. Renal biopsy showed acute interstitial nephritis associated with nonsteroid anti-inflammatory drug (NSAID). After discontinuing the medication, urinoma subsided, and the patient was discharged with normal serum creatinine. This was the first case of urinoma induced by NSAID-related interstitial nephritis, and pathophysiology and management of spontaneous urinoma are discussed.
尿囊肿是指尿液渗漏至尿路以外，通常由钝性创伤或结石、腹腔内恶性肿瘤或腹膜后纤维化导致的尿路梗阻引起。自发性尿囊肿很少见，发现尿囊肿时很少提及实质病理改变。我们报告一例28岁女性因自发性尿囊肿引起双侧胁腹疼痛的病例。该女士因偏头痛长期服用镇痛药。静脉注射酮咯酸后，双侧肾周出现尿囊肿。肾活检显示急性间质性肾炎与非甾体抗炎药（NSAID）有关。停药后，尿囊肿消退，患者血清肌酐正常出院。这是首例由NSAID相关性间质性肾炎引起的尿囊肿病例，并对自发性尿囊肿的病理生理学和治疗进行了讨论。
