Institute of Structural and Molecular Biology, University College London, London, UK.
Institute of Structural and Molecular Biology, University College London, London, UK.
Structure. 2018 Apr 3;26(4):528-530. doi: 10.1016/j.str.2018.03.009.
In this issue of Structure, Tyzack et al. (2018) present a study of enzyme-ligand complexes in the PDB and show that the molecular similarity of bound and cognate ligands can be used to choose the most biologically appropriate complex structure for analysis when multiple structures are available.
在本期《结构》中,Tyzack 等人(2018 年)研究了 PDB 中的酶-配体复合物,并表明当有多个结构可用时,结合配体和同源配体的分子相似性可用于选择最适合生物学分析的复合物结构。