Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Clin Infect Dis. 2018 Apr 3;66(suppl_3):S173-S182. doi: 10.1093/cid/cix951.
The World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) have set a Fast-Track goal to achieve 90% coverage of voluntary medical male circumcision (VMMC) among boys and men aged 10-29 years in priority settings by 2021. We aimed to identify age-specific facilitators of VMMC uptake among adolescents.
Younger (aged 10-14 years; n = 967) and older (aged 15-19 years; n = 559) male adolescents completed structured interviews about perceptions of and motivations for VMMC before receiving VMMC counseling at 14 service provision sites across South Africa, Tanzania, and Zimbabwe. Adjusted prevalence ratios (aPRs) were estimated using multivariable modified Poisson regression models with generalized estimating equations and robust standard errors.
The majority of adolescents reported a strong desire for VMMC. Compared with older adolescents, younger adolescents were less likely to cite protection against human immunodeficiency virus (HIV) or other sexually transmitted infections (aPR, 0.77; 95% confidence interval [CI], .66-.91) and hygienic reasons (aPR, 0.55; 95% CI, .39-.77) as their motivation to undergo VMMC but were more likely to report being motivated by advice from others (aPR, 1.88; 95% CI, 1.54-2.29). Although most adolescents believed that undergoing VMMC was a normative behavior, younger adolescents were less likely to perceive higher descriptive norms (aPR, 0.79; .71-.89), injunctive norms (aPR, 0.86; 95% CI, .73-1.00), or anticipated stigma for being uncircumcised (aPR, 0.79; 95% CI, .68-.90). Younger adolescents were also less likely than older adolescents to correctly cite that VMMC offers men and boys partial HIV protection (aPR, 0.73; 95% CI, .65-.82). Irrespective of age, adolescents' main concern about undergoing VMMC was pain (aPR, 0.95; 95% CI, .87-1.04). Among younger adolescents, fear of pain was negatively associated with desire for VMMC (aPR, 0.89; 95% CI, .83-.96).
Age-specific strategies are important to consider to generate sustainable demand for VMMC. Programmatic efforts should consider building on the social norms surrounding VMMC and aim to alleviate fears about pain.
世界卫生组织(WHO)和联合国艾滋病规划署(UNAIDS)设定了一个快速通道目标,即在 2021 年之前,在重点地区实现 90%的 10-29 岁男孩和男子接受自愿医疗男性包皮环切术(VMMC)。我们旨在确定青少年接受 VMMC 的特定年龄促进因素。
在南非、坦桑尼亚和津巴布韦的 14 个服务提供点,年龄较小(10-14 岁;n = 967)和年龄较大(15-19 岁;n = 559)的男青少年在接受 VMMC 咨询前完成了关于 VMMC 的看法和动机的结构化访谈。使用具有广义估计方程和稳健标准误差的多变量修正泊松回归模型估计调整后患病率比(aPR)。
大多数青少年表示强烈希望接受 VMMC。与年龄较大的青少年相比,年龄较小的青少年不太可能将保护免受人类免疫缺陷病毒(HIV)或其他性传播感染(aPR,0.77;95%置信区间[CI],0.66-0.91)和卫生原因(aPR,0.55;95%CI,0.39-0.77)作为他们接受 VMMC 的动机,但更有可能报告受到他人建议的激励(aPR,1.88;95%CI,1.54-2.29)。尽管大多数青少年认为接受 VMMC 是一种规范行为,但年龄较小的青少年不太可能感知到更高的描述性规范(aPR,0.79;0.71-0.89)、规范性规范(aPR,0.86;95%CI,0.73-1.00)或对未行包皮环切术的预期耻辱(aPR,0.79;0.68-0.90)。年龄较小的青少年也比年龄较大的青少年更不可能正确地指出 VMMC 为男性和男孩提供部分 HIV 保护(aPR,0.73;95%CI,0.65-0.82)。无论年龄大小,青少年对接受 VMMC 的主要担忧是疼痛(aPR,0.95;95%CI,0.87-1.04)。在年龄较小的青少年中,对疼痛的恐惧与对 VMMC 的渴望呈负相关(aPR,0.89;95%CI,0.83-0.96)。
考虑到特定年龄的策略很重要,以产生对 VMMC 的可持续需求。规划工作应考虑围绕 VMMC 建立社会规范,并努力减轻对疼痛的恐惧。