Morrow W R, Vick G W, Nihill M R, Rokey R, Johnston D L, Hedrick T D, Mullins C E
Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children's Hospital, Houston 77030.
J Am Coll Cardiol. 1988 Jan;11(1):133-8. doi: 10.1016/0735-1097(88)90178-7.
Balloon dilation is effective in the immediate relief of obstruction due to unoperated coarctation of the aorta. However, the long-term benefits and complications of this procedure have not been established. Thirty-three patients underwent balloon dilation of unoperated coarctation using a percutaneous technique from November 1983 to December 1985. High quality biplane angiography was performed before and after dilation. Follow-up was obtained in 20 patients from 6 to 31 months following dilation. Angiography was performed at follow-up in 10, nuclear magnetic resonance (NMR) imaging in 10 and both NMR imaging and angiography in 3. Balloon dilation was successful in 31 of the 33 patients with a decrease in average systolic pressure gradient from 46 to 8 mm Hg. There was no significant change in gradient on follow-up physical examination and at recatheterization in 10 patients. In addition, there was no evidence of restenosis on follow-up angiography and NMR imaging. In two patients, a small aneurysm formed at the site of balloon dilation. Balloon dilation of unoperated coarctation is effective, providing lasting relief of coarctation gradient and no evidence of restenosis. However, because of the uncertain natural history of aneurysms after dilation, this procedure should be considered investigational until further follow-up on patients with and without an aneurysm is available.
球囊扩张术对于因未经手术治疗的主动脉缩窄所致梗阻的即刻缓解是有效的。然而,该手术的长期益处和并发症尚未明确。1983年11月至1985年12月,33例患者采用经皮技术对未经手术治疗的主动脉缩窄进行了球囊扩张。扩张前后均进行了高质量的双平面血管造影。对20例患者在扩张后6至31个月进行了随访。10例患者在随访时进行了血管造影,10例进行了核磁共振(NMR)成像,3例同时进行了核磁共振成像和血管造影。33例患者中有31例球囊扩张成功,平均收缩压梯度从46 mmHg降至8 mmHg。10例患者随访体格检查及再次心导管检查时梯度无显著变化。此外,随访血管造影和核磁共振成像均未发现再狭窄证据。2例患者在球囊扩张部位形成了小动脉瘤。未经手术治疗的主动脉缩窄球囊扩张术是有效的,可持久缓解缩窄梯度且无再狭窄证据。然而,由于扩张后动脉瘤的自然病史不确定,在对有或无动脉瘤患者进行进一步随访之前,该手术应被视为试验性的。