Sadeghi Mohammad Hosein, Sina Sedigheh, Mehdizadeh Amir, Faghihi Reza, Moharramzadeh Vahed, Meigooni Ali Soleimani
Department of Nuclear Engineering, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.
Radiation Research Center, Shiraz University, Shiraz, Iran.
J Contemp Brachytherapy. 2018 Feb;10(1):91-95. doi: 10.5114/jcb.2018.74314. Epub 2018 Feb 28.
The dosimetry procedure by simple superposition accounts only for the self-shielding of the source and does not take into account the attenuation of photons by the applicators. The purpose of this investigation is an estimation of the effects of the tandem and ovoid applicator on dose distribution inside the phantom by MCNP5 Monte Carlo simulations.
In this study, the superposition method is used for obtaining the dose distribution in the phantom without using the applicator for a typical gynecological brachytherapy (superposition-1). Then, the sources are simulated inside the tandem and ovoid applicator to identify the effect of applicator attenuation (superposition-2), and the dose at points A, B, bladder, and rectum were compared with the results of superposition. The exact dwell positions, times of the source, and positions of the dosimetry points were determined in images of a patient and treatment data of an adult woman patient from a cancer center. The MCNP5 Monte Carlo (MC) code was used for simulation of the phantoms, applicators, and the sources.
The results of this study showed no significant differences between the results of superposition method and the MC simulations for different dosimetry points. The difference in all important dosimetry points was found to be less than 5%.
According to the results, applicator attenuation has no significant effect on the calculated points dose, the superposition method, adding the dose of each source obtained by the MC simulation, can estimate the dose to points A, B, bladder, and rectum with good accuracy.
简单叠加剂量计算程序仅考虑了源的自屏蔽,未考虑施源器对光子的衰减。本研究的目的是通过MCNP5蒙特卡罗模拟评估串联和卵圆型施源器对模体内剂量分布的影响。
在本研究中,叠加法用于在不使用施源器的情况下获得典型妇科近距离治疗模体内的剂量分布(叠加-1)。然后,在串联和卵圆型施源器内模拟源,以确定施源器衰减的影响(叠加-2),并将A点、B点、膀胱和直肠处的剂量与叠加结果进行比较。在来自癌症中心的成年女性患者的图像和治疗数据中确定源的精确驻留位置、驻留时间以及剂量测量点的位置。使用MCNP5蒙特卡罗(MC)代码对模体、施源器和源进行模拟。
本研究结果表明,叠加法结果与不同剂量测量点的MC模拟结果之间无显著差异。发现所有重要剂量测量点的差异均小于5%。
根据结果,施源器衰减对计算的点剂量无显著影响,叠加法通过添加MC模拟获得的每个源的剂量,可以准确地估计A点、B点、膀胱和直肠处的剂量。