裸鼠系统在人类子宫内膜癌肿瘤生物学、治疗策略及孕激素受体生理学研究中的应用
Nude mouse system in the study of tumor biology, treatment strategies and progesterone receptor physiology in human endometrial carcinoma.
作者信息
Satyaswaroop P G, Zaino R, Clarke C L, Mortel R
机构信息
Department of Obstetrics and Gynecology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
出版信息
J Steroid Biochem. 1987;27(1-3):431-8. doi: 10.1016/0022-4731(87)90337-2.
PMID:2961935
Abstract
A nude mouse system where the biological, morphological and biochemical characteristics of human endometrial carcinoma are maintained during serial transplantation has been previously described. Applications of this system to the study of (a) hormonal sensitivity (b) treatment strategies and (c) progesterone receptor physiology of human endometrial carcinomas are presented here.
摘要
先前已描述了一种裸鼠系统，在连续移植过程中该系统能维持人子宫内膜癌的生物学、形态学和生化特征。本文介绍了该系统在研究人子宫内膜癌的（a）激素敏感性、（b）治疗策略和（c）孕激素受体生理学方面的应用。
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