Allam Ghada, Ellakkany Rasheed, Ellayeh Adel, Mohsen Tarek, Abouelkheir Hossam ElDin, Gaafar Walid
Department of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Eur J Ophthalmol. 2018 Nov;28(6):633-638. doi: 10.1177/1120672117754168. Epub 2018 Apr 5.
: To evaluate the use of intraocular injection of triamcinolone acetonide in pediatric cataract surgery with or without intraocular lens implantation as a vitreous dye to ensure a complete anterior vitrectomy and evaluate its effect on postoperative ocular inflammation, infection, posterior capsule opacification, and intraocular pressure.
: Randomized controlled trial included children diagnosed with bilateral congenital cataract in both eyes. Their eyes were randomly assigned into two groups: group A underwent aspiration, posterior capsulotomy, and anterior vitrectomy with intraocular injection of triamcinolone acetonide, while group B underwent the same surgical procedure without intraocular injection of triamcinolone acetonide. Intraocular pressure, postoperative inflammation, infection, and posterior capsule opacification were followed up till 6 months.
: The study comprised 44 eyes of 22 children. The mean age was 2.4 ± 2.1 years including 10 males and 12 females. The mean postoperative intraocular pressure was within normal range in both groups. No case of infection in both groups. No eyes in group A showed reaction, while in group B, three eyes showed exudate on the first day, which improved at 2 weeks. Posterior synechiae was recorded in four eyes in group A and in five eyes in group B. Posterior capsule opacification was noted in one eye in group A at 3 month, while it was noted in nine eyes in group B. The difference was statistically significant ( p = 0.004).
: Triamcinolone acetonide was found to be useful in better visualization of vitreous in pediatric cataract surgery and has good effect in decreasing postoperative inflammation and posterior capsule opacification.
评估在小儿白内障手术中，无论是否植入人工晶状体，眼内注射曲安奈德作为玻璃体染色剂以确保彻底的前部玻璃体切除术，并评估其对术后眼部炎症、感染、后囊膜混浊和眼压的影响。
随机对照试验纳入双眼诊断为双侧先天性白内障的儿童。他们的眼睛被随机分为两组：A组接受抽吸、后囊切开术和前部玻璃体切除术，并眼内注射曲安奈德，而B组接受相同的手术操作但不进行眼内注射曲安奈德。随访眼压、术后炎症、感染和后囊膜混浊直至6个月。
该研究包括22名儿童的44只眼。平均年龄为2.4±2.1岁，其中男性10名，女性12名。两组术后平均眼压均在正常范围内。两组均无感染病例。A组无眼出现反应，而B组有3只眼在第一天出现渗出物，在2周时有所改善。A组有4只眼记录有虹膜后粘连，B组有5只眼。A组有1只眼在3个月时出现后囊膜混浊，而B组有9只眼。差异有统计学意义（p = 0.004）。
发现曲安奈德在小儿白内障手术中有助于更好地观察玻璃体，并且在减轻术后炎症和后囊膜混浊方面有良好效果。
