Ray Ujjwayini, Dutta Soma, Chakravarty Chandrashish
Southeast Asian J Trop Med Public Health. 2016 Sep;47(5):1026-31.
Cladophialophora bantiana is a dematiceous fungus with neurotrophic propensity for which therapy is not standardized and mortality is high. We report here a 49 year old non-diabetic renal transplant patient on triple immunosuppressant therapy who presented with a history of falls, weakness and headaches. A computed tomography scan of the brain revealed a 30 mm diameter abscess in the brain which was removed surgically and diagnosed on culture as C. bantiana. The patient was successfully treated medically post-operatively with chronic posaconazole. We review the literature regarding central nervous system infections due to C. bantiana.
班替枝孢霉是一种具有嗜神经性的暗色真菌,其治疗方法尚未标准化,死亡率很高。我们在此报告一名49岁的非糖尿病肾移植患者,该患者正在接受三联免疫抑制治疗,出现了跌倒、虚弱和头痛的病史。脑部计算机断层扫描显示脑部有一个直径30毫米的脓肿,通过手术切除,并在培养后诊断为班替枝孢霉。该患者术后通过长期服用泊沙康唑成功接受了药物治疗。我们回顾了关于班替枝孢霉引起的中枢神经系统感染的文献。