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巴勒斯坦各类医院急诊科急性中毒暴露与中毒管理治疗资源的可及性:一项横断面研究

Availability of treatment resources for the management of acute toxic exposures and poisonings in emergency departments among various types of hospitals in Palestine: a cross-sectional study.

作者信息

Zyoud Sa'ed H, Al-Jabi Samah W, Bali Yara I, Al-Sayed Afnan M, Sweileh Waleed M, Awang Rahmat

机构信息

Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

出版信息

Scand J Trauma Resusc Emerg Med. 2014 Feb 21;22:13. doi: 10.1186/1757-7241-22-13.

Abstract

BACKGROUND

Poisoning exposures continue to be a significant cause of morbidity and mortality worldwide. The lack of facilities, treatment resources, and antidotes in hospitals may affect the treatments provided and outcomes. This study aimed to determine the availability of gastrointestinal (GI) decontamination, stabilisation, elimination enhancement resources, and antidotes for the management of acute toxic exposures and poisonings in emergency departments (EDs) among various types of governmental and private hospitals in Palestine.

METHODS

A cross-sectional study using semi-structured questionnaire was performed. Data were collected based on hospital resources; GI decontamination, stabilisation, elimination enhancement resources and antidotes from Palestinian hospitals.

RESULTS

Eighteen hospitals (94.7%) have responded. Among them, paracetamol poisoning was the most frequently reported cases by EDs (mean frequency score = 7.6 ± 2.1), followed by bee stings (mean = 6.9 ± 2.7) and organophosphate poisoning (mean = 6.7 ± 2.7). The availabilities of most resources related to GI decontamination items varied substantially with hospital type, but these differences were not statistical significant. The availability of stabilisation resources was not significantly different between hospitals types. For the availability of techniques used to enhance the elimination of toxic substances, there were variations between the hospitals types. However, these differences were not statistical significant, except for haemodialysis (p = 0.003) which was more available in governmental hospitals. For the availability of antidotes, none of the hospitals had sufficient stock of all antidotes listed. In relation to hospital type, there was variability in the availability of antidotes, but this did not reach statistical significance, except for deferoxamine (p < 0.001), which was available in all governmental hospitals but none of the private hospitals.

CONCLUSIONS

The availability of treatment resources and antidotes in Palestinian hospitals was not adequate except for stabilisation resources. The availability of such resources acts as a marker for the level of readiness of hospital EDs in Palestine for the management of acute toxic exposure and poisoning. The implementation of a minimum list of antidotes and treatment resources would be useful to increase the level of resources. Coordination between Palestinian poison control and drug information centre and hospitals is also important.

摘要

背景

中毒暴露仍是全球发病和死亡的重要原因。医院缺乏设施、治疗资源和解毒剂可能会影响所提供的治疗及治疗结果。本研究旨在确定巴勒斯坦各类政府和私立医院急诊科用于急性中毒暴露和中毒管理的胃肠道(GI)去污、稳定、促进消除资源及解毒剂的可获得性。

方法

采用半结构化问卷进行横断面研究。基于医院资源收集数据;来自巴勒斯坦医院的GI去污、稳定、促进消除资源及解毒剂。

结果

18家医院(94.7%)做出了回应。其中,对乙酰氨基酚中毒是急诊科报告最多的病例(平均频率得分=7.6±2.1),其次是蜂蜇伤(平均=6.9±2.7)和有机磷中毒(平均=6.7±2.7)。大多数与GI去污项目相关资源的可获得性因医院类型而异,但这些差异无统计学意义。稳定资源的可获得性在不同医院类型之间无显著差异。对于用于促进有毒物质消除的技术的可获得性,不同医院类型之间存在差异。然而,这些差异无统计学意义,除了血液透析(p=0.003),其在政府医院更易获得。对于解毒剂的可获得性,没有一家医院备有所有列出解毒剂的充足库存。就医院类型而言,解毒剂的可获得性存在差异,但未达到统计学意义,除了去铁胺(p<0.001),其在所有政府医院都有,但私立医院均无。

结论

除稳定资源外,巴勒斯坦医院的治疗资源和解毒剂可获得性不足。此类资源的可获得性是巴勒斯坦医院急诊科应对急性中毒暴露和中毒管理准备水平的一个标志。实施最低限度的解毒剂和治疗资源清单将有助于提高资源水平。巴勒斯坦毒物控制与药物信息中心与医院之间的协调也很重要。

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