Vitanova L, Penchev A, Kupenova P, Belcheva S
Department of Physiology, Medical Academy, Sofia, Bulgaria.
Physiol Bohemoslov. 1987;36(5):463-70.
The intensity-response function of the b-wave of the ERG in the retina of the turtle (Emys orbicularis) was investigated at two different background illuminations--0.01 and 10 lx, before and after blockade of the GABA-ergic transmission by 0.4 mmol/l picrotoxin (PT). A shift of the curve to the left along the intensity axis at both backgrounds was observed after PT treatment. The region where the b-wave amplitude was linear function of the logarithm of the stimulus intensity was also considerably narrowed. The registered experimental data fitted in well with the Naka-Rushton equation. The participation of GABA-ergic neurones in the processes of light adaptation and gain control in the retina is discussed.
在0.01和10勒克斯这两种不同背景光照条件下，研究了乌龟（圆 orbicularis）视网膜中视网膜电图b波的强度 - 反应函数，实验在0.4毫摩尔/升苦味毒（PT）阻断GABA能传递之前和之后进行。PT处理后，在两种背景下均观察到曲线沿强度轴向左移动。b波振幅是刺激强度对数的线性函数的区域也显著变窄。记录的实验数据与中纳 - 拉什顿方程拟合良好。讨论了GABA能神经元在视网膜光适应和增益控制过程中的作用。
