Fujita Akifumi
Department of Radiology, Jichi Medical University School of Medicine, 3311-1, Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.
Neuroimaging Clin N Am. 2018 May;28(2):183-197. doi: 10.1016/j.nic.2018.01.003.
The salivary glands are commonly affected in systemic autoimmune disease and diseases of unknown pathogenesis. Sjögren syndrome (SjS) can be affected by other systemic diseases. Immunoglobulin G4-related disease (IgG4-RD) commonly affects salivary glands. Imaging findings are usually nonspecific; however, radiologists should be familiar with the manifestations to avoid diagnostic delay. Findings of early-stage SjS are difficult to identify on routine computed tomography or MR imaging. Chronic SjS can be diagnosed from MR imaging and sialographic findings. Multiglandular and localized involvement of IgG4-RD is difficult to differentiate from malignant lymphoma for multiglandular disease and salivary gland carcinoma for localized disease.
唾液腺在系统性自身免疫性疾病和发病机制不明的疾病中常受到影响。干燥综合征（SjS）可受其他全身性疾病影响。免疫球蛋白G4相关疾病（IgG4-RD）常累及唾液腺。影像学表现通常不具有特异性；然而，放射科医生应熟悉这些表现以避免诊断延误。早期SjS的表现难以在常规计算机断层扫描或磁共振成像上识别。慢性SjS可根据磁共振成像和唾液造影结果进行诊断。IgG4-RD的多腺性和局限性受累，对于多腺性疾病难以与恶性淋巴瘤相鉴别，对于局限性疾病难以与唾液腺癌相鉴别。
