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从一名中性粒细胞减少症患者血液中分离出的拟哈氏假丝酵母的基因组序列草图

Draft Genome Sequence of Candida pseudohaemulonii Isolated from the Blood of a Neutropenic Patient.

作者信息

Mohd Tap Ratna, Kamarudin Nur Amalina, Ginsapu Stephanie Jane, Ahmed Bakri Ahmed Rafezzan, Ahmad Norazah, Amran Fairuz, Sipiczki Matthias

机构信息

Mycology Laboratory, Bacteriology Unit, Infectious Diseases Research Centre, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia

Mycology Laboratory, Bacteriology Unit, Infectious Diseases Research Centre, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.

出版信息

Genome Announc. 2018 Apr 5;6(14):e00166-18. doi: 10.1128/genomeA.00166-18.

DOI:10.1128/genomeA.00166-18
PMID:29622608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5887024/
Abstract

is phylogenetically close to the complex and exhibits resistance to amphotericin B and azole agents. We report here the draft genome sequence of UZ153_17 isolated from the blood culture of a neutropenic patient. The draft genome is 3,532,003,666 bp in length, with 579,838 reads, 130 contigs, and a G+C content of 47.15%.

摘要

在系统发育上与该复合体接近，并且对两性霉素B和唑类药物具有抗性。我们在此报告从一名中性粒细胞减少患者的血培养物中分离出的UZ153_17的基因组草图序列。该基因组草图长度为3,532,003,666 bp，有579,838条读数，130个重叠群，G+C含量为47.15%。

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本文引用的文献

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Reclassification of the Candida haemulonii complex as Candida haemulonii (C. haemulonii group I), C. duobushaemulonii sp. nov. (C. haemulonii group II), and C. haemulonii var. vulnera var. nov.: three multiresistant human pathogenic yeasts.将半滑舌鳎球拟酵母复合体重新分类为半滑舌鳎球拟酵母（半滑舌鳎球拟酵母 I 群）、双相半滑舌鳎球拟酵母新种（半滑舌鳎球拟酵母 II 群）和半滑舌鳎球拟酵母脆弱变种新变种：三种多药耐药的人类致病性酵母。
J Clin Microbiol. 2012 Nov;50(11):3641-51. doi: 10.1128/JCM.02248-12. Epub 2012 Sep 5.
2
MAKER2: an annotation pipeline and genome-database management tool for second-generation genome projects.MAKER2：用于第二代基因组项目的注释流水线和基因组数据库管理工具。
BMC Bioinformatics. 2011 Dec 22;12:491. doi: 10.1186/1471-2105-12-491.
3
Extraction of genomic DNA from yeasts for PCR-based applications.从酵母中提取基因组 DNA 用于基于 PCR 的应用。
Biotechniques. 2011 May;50(5):325-8. doi: 10.2144/000113672.
4
SOAP: short oligonucleotide alignment program.SOAP：短寡核苷酸比对程序。
Bioinformatics. 2008 Mar 1;24(5):713-4. doi: 10.1093/bioinformatics/btn025. Epub 2008 Jan 28.
5
Candida pseudohaemulonii Sp. Nov., an amphotericin B-and azole-resistant yeast species, isolated from the blood of a patient from Thailand.新型假海氏念珠菌，一种对两性霉素B和唑类耐药的酵母菌种，从一名泰国患者的血液中分离得到。
Microbiol Immunol. 2006;50(6):469-73. doi: 10.1111/j.1348-0421.2006.tb03816.x.