Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Med Mycol. 2011 Jan;49(1):98-102. doi: 10.3109/13693786.2010.493563. Epub 2010 Jun 21.
Emergence of Candida haemulonii and closely related species at five Korean hospitals has been recently described. We examined biofilm formation by these isolates and assessed their genotypic relatedness by pulsed-field gel electrophoresis (PFGE). This study is the first to show that all bloodstream isolates of Candida pseudohaemulonii can form significant biofilms in glucose-containing medium. PFGE of NotI-digested genomic DNA revealed that C. pseudohaemulonii isolates recovered from seven patients in two hospitals shared five patterns, and that 15 isolates of a proposed new species (Candida auris) obtained from patients at three hospitals shared seven patterns, suggesting that some of these isolates may be related to clonal transmission.
最近有报道称，在韩国的五家医院中出现了近平滑假丝酵母和与其密切相关的物种。我们检测了这些分离株的生物膜形成能力，并通过脉冲场凝胶电泳 (PFGE) 评估了它们的基因型相关性。这项研究首次表明，所有来自血液的近平滑假丝酵母分离株都可以在含有葡萄糖的培养基中形成显著的生物膜。诺特 I 酶切基因组 DNA 的 PFGE 显示，从两家医院的七名患者中分离出的近平滑假丝酵母分离株共享五种模式，而从三家医院的患者中分离出的 15 株拟议的新物种（耳念珠菌）共享七种模式，表明其中一些分离株可能与克隆传播有关。
