多重耐药性：沙特阿拉伯王国阿西尔地区新出现的健康威胁。
Multidrug-Resistant : An Emerging Health Threat in Aseer Region, Kingdom of Saudi Arabia.
作者信息
Almaghrabi Mohammed K, Joseph Martin R P, Assiry Mohammed M, Hamid Mohamed E
机构信息
Department of Microbiology and Clinical Parasitology, King Khalid University, Abha, Saudi Arabia.
Microbiology Laboratories, Aseer Central Hospital, Abha, Saudi Arabia.
出版信息
Can J Infect Dis Med Microbiol. 2018 Feb 4;2018:9182747. doi: 10.1155/2018/9182747. eCollection 2018.
OBJECTIVE
The study aims to determine the prevalence of multidrug-resistant in Aseer Region, Kingdom of Saudi Arabia.
METHODS
This study evaluated the antibiotic susceptibility of ninety-four ( = 94) clinical isolates of . The isolates were collected from the south region of Saudi Arabia, and notably Aseer Region, during the period from 15 October 2014 to 15 January 2015. The isolates were tentatively identified as by routine bench tests and were confirmed by using VITEK® 2 Compact. The latest instrument was used to identify antibiotic susceptibility of these isolates.
RESULTS
Antibiotic susceptibility in this study showed that 69% of these isolates were multidrug-resistant strains. Moreover, they were highly resistant to carbapenem drugs. Several strains of these isolates were found to be extremely resistant to test antibiotics and were only sensitive to one or two of them.
CONCLUSION
High rate of multidrug-resistant bacteraemia has emerged in the south region of Saudi Arabia as an important health problem. Therefore, it is considered as a new threat in hospitals, which requires a tremendous effort to stop its escalation and spread.
目的
本研究旨在确定沙特阿拉伯王国阿西尔地区多重耐药菌的流行情况。
方法
本研究评估了94株[具体细菌名称未给出]临床分离株的抗生素敏感性。这些分离株于2014年10月15日至2015年1月15日期间从沙特阿拉伯南部地区，特别是阿西尔地区采集。通过常规实验室检测初步鉴定这些分离株，并使用VITEK® 2 Compact进行确认。使用最新仪器鉴定这些分离株的抗生素敏感性。
结果
本研究中的抗生素敏感性表明，69%的这些分离株为多重耐药菌株。此外，它们对碳青霉烯类药物高度耐药。发现这些分离株中的几株对测试抗生素具有极高的耐药性，仅对其中一两种敏感。
结论
沙特阿拉伯南部地区出现的多重耐药菌菌血症高发生率已成为一个重要的健康问题。因此，它被视为医院中的一种新威胁，需要付出巨大努力来阻止其升级和传播。
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