Gudis David A, Soler Zachary M
Department of Otolaryngology - Head and Neck Surgery, Columbia University Medical Center, New York, NY.
Department of Otolaryngology-Head and Neck Surgery, Division of Rhinology and Sinus Surgery, Medical University of South Carolina, Charleston, SC.
Curr Otorhinolaryngol Rep. 2016 Jun;4(2):142-147. doi: 10.1007/s40136-016-0114-4. Epub 2016 Apr 8.
Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nasal cavities and paranasal sinuses. Olfactory dysfunction is a common manifestation of CRS and one of its cardinal diagnostic features. A decreased sense of smell can have a profound impact on a CRS patient's quality of life and overall wellbeing. The treatment of CRS-associated olfactory dysfunction includes a wide range of medical interventions, including anti-inflammatory and antibiotic medications, and surgical interventions, including endoscopic sinus and nasal surgery. The evidence and treatment efficacy for these interventions is quite varied. This review provides a summary of the efficacy of the medical and surgical therapeutic options for CRS-associated olfactory dysfunction.
慢性鼻-鼻窦炎（CRS）是鼻腔和鼻窦的一种炎症性疾病。嗅觉功能障碍是CRS的常见表现及其主要诊断特征之一。嗅觉减退会对CRS患者的生活质量和整体健康产生深远影响。CRS相关嗅觉功能障碍的治疗包括多种医学干预措施，如抗炎和抗生素药物治疗，以及手术干预措施，如鼻内镜鼻窦和鼻腔手术。这些干预措施的证据和治疗效果差异很大。本综述总结了CRS相关嗅觉功能障碍的医学和手术治疗选择的疗效。
