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细菌色素的治疗应用:现状与未来机遇综述

Therapeutic applications of bacterial pigments: a review of current status and future opportunities.

作者信息

Numan Muhammad, Bashir Samina, Mumtaz Roqayya, Tayyab Sibgha, Rehman Najeeb Ur, Khan Abdul Latif, Shinwari Zabta Khan, Al-Harrasi Ahmed

机构信息

1Department of Biotechnology, Quaid-i-Azam University, Islamabad, 45320 Pakistan.

2UoN Chair of Oman's Medicinal Plants and Marine Natural Products, University of Nizwa, Nizwa-616, Sultanate of Oman, Nizwa-616, Birkat Al Mauz, P.O Box 33, 616 Nizwa, Oman.

出版信息

3 Biotech. 2018 Apr;8(4):207. doi: 10.1007/s13205-018-1227-x. Epub 2018 Apr 4.

Abstract

Non-toxicity, biodegradability and non-carcinogenicity of the natural pigments, dyes and colorants make them an attractive source for human use. Bacterial pigments are colored metabolites secreted by bacteria under stress. The industrial uses of bacterial pigments have increased many folds because of several advantages over the synthetic pigments. Among natural resources, bacterial pigments are mostly preferred because of simple culturing and pigment extraction techniques, scaling up and being time economical. Generally, the bacterial pigments are safe for human use and therefore have a wide range of applications in pharmaceutical, textile, cosmetics and food industries. Therapeutic nature of the bacterial pigments is revealed because of their antimicrobial, anticancer, cytotoxic and remarkable antioxidant properties. Owing to the importance of bacterial pigments it was considered important to produce a comprehensive review of literature on the therapeutic and industrial potential of bacterial pigments. Extensive literature has been reviewed on the biomedical application of bacterial pigments while further opportunities and future challenges have been discussed.

摘要

天然色素、染料和着色剂的无毒、可生物降解和非致癌性使其成为人类使用的有吸引力的来源。细菌色素是细菌在应激状态下分泌的有色代谢产物。由于细菌色素相对于合成色素具有多种优势,其工业用途已增长了许多倍。在自然资源中,细菌色素因其培养和色素提取技术简单、易于扩大规模且节省时间而最为常用。一般来说,细菌色素对人类使用是安全的,因此在制药、纺织、化妆品和食品工业中有广泛的应用。细菌色素的抗菌、抗癌、细胞毒性和显著的抗氧化特性揭示了其治疗性质。鉴于细菌色素的重要性,对有关细菌色素治疗和工业潜力的文献进行全面综述被认为很重要。本文对细菌色素的生物医学应用进行了广泛的文献综述,并讨论了进一步的机遇和未来的挑战。

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Endophytic bacteria: a new source of bioactive compounds.内生细菌:生物活性化合物的新来源。
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