Emil Fisher Center, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 9, 91054, Erlangen, Germany.
Department Sensory Analytics, Fraunhofer Institute for Process Engineering and Packaging, Giggenhauser Straße 35, 85354, Freising, Germany.
Anal Bioanal Chem. 2018 May;410(14):3395-3404. doi: 10.1007/s00216-018-1046-2. Epub 2018 Apr 6.
Elastic therapeutic tapes are an important tool in the field of physical therapy and medicine. These tapes contain types of adhesive. However, sensory evaluations revealed the release of pronounced and irritating odors of the tapes. Negative odors were, amongst others, reported in elastic therapeutic tapes containing acrylic adhesives. In this study, the odor of four different tape samples was evaluated applying a descriptive analysis approach carried out by a trained sensory panel. Afterwards, the volatile compounds were recovered from the samples by solvent extraction and isolated by solvent-assisted flavor evaporation (SAFE). The obtained distillates were subsequently analyzed by gas chromatography-olfactometry (GC-O) and two-dimensional GC-O coupled with mass spectrometry (2D-GC-MS/O). To determine the most potent odorants in the distillates, odor extract dilution analyses (OEDA) were carried out. Thirty-one odorants were successfully identified using this approach, which were all described for the first time as odorants in tapes. Amongst the set of volatiles, unsaturated and saturated aldehydes were present, eliciting fatty, soapy, and citrus-like odor impressions, as well as a range of glue-like, moldy, and fruity smelling odor-active volatiles, such as 2-ethyl-1-hexanol, butyl benzoate, and 3-phenyltoluene. Based on their relative intensities, the concentrations of the glue-like smelling substances were determined: 2-ethyl-1-hexanol, present in all samples, was determined with concentrations ranging from 10 to 200 mg/kg in the investigated tapes.
弹性治疗带是物理治疗和医学领域的重要工具。这些带含有各种类型的粘合剂。然而，感官评估显示这些带会释放出明显的刺激性气味。含有丙烯酸粘合剂的弹性治疗带报告了负面气味。在这项研究中，应用经过训练的感官小组进行的描述性分析方法评估了四种不同的胶带样品的气味。然后，通过溶剂萃取从样品中回收挥发性化合物，并通过溶剂辅助风味蒸发（SAFE）进行分离。获得的馏出物随后通过气相色谱-嗅觉分析（GC-O）和二维 GC-O 与质谱（2D-GC-MS/O）进行分析。为了确定馏出物中最有效的气味剂，进行了气味提取稀释分析（OEDA）。使用这种方法成功鉴定了 31 种气味剂，这些气味剂均首次被描述为带中的气味剂。在所研究的挥发性物质中，存在不饱和和饱和醛类，产生脂肪、肥皂和柑橘类的气味印象，以及一系列胶水味、发霉味和水果味的气味活性挥发性物质，如 2-乙基-1-己醇、苯甲酸丁酯和 3-苯基甲苯。基于它们的相对强度，确定了胶水味物质的浓度：在所有样品中都存在的 2-乙基-1-己醇，在所研究的带中浓度范围为 10 至 200mg/kg。
