Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
J Hosp Med. 2018 Apr;13(4):263-271. doi: 10.12788/jhm.2980.
Hospital-based clinicians frequently treat acute, noncancer pain. Although opioids may be beneficial in this setting, the benefits must be balanced with the risks of adverse events, including inadvertent overdose and prolonged opioid use, physical dependence, or development of opioid use disorder. In an era of epidemic opioid use and related harms, the Society of Hospital Medicine (SHM) convened a working group to develop a consensus statement on opioid use for adults hospitalized with acute, noncancer pain, outside of the palliative, end-of-life, and intensive care settings. The guidance is intended for clinicians practicing medicine in the inpatient setting (eg, hospitalists, primary care physicians, family physicians, nurse practitioners, and physician assistants). To develop the Consensus Statement, the working group conducted a systematic review of relevant guidelines, composed a draft Statement based on extracted recommendations, and obtained feedback from external experts in hospital-based opioid prescribing, SHM members, the SHM Patient-Family Advisory Council, other professional societies, and peer-reviewers. The iterative development process resulted in a final Consensus Statement consisting of 16 recommendations covering 1) whether to use opioids in the hospital, 2) how to improve the safety of opioid use during hospitalization, and 3) how to improve the safety of opioid prescribing at hospital discharge. As most guideline recommendations from which the Consensus Statement was derived were based on expert opinion alone, the working group identified key issues for future research to support evidence-based practice.
医疗机构的临床医生经常治疗急性非癌性疼痛。虽然在这种情况下使用阿片类药物可能是有益的,但必须权衡其益处与不良反应风险,包括意外过量和延长阿片类药物使用、身体依赖或阿片类药物使用障碍的发展。在阿片类药物使用流行和相关危害的时代,医院医学学会(SHM)召集了一个工作组,制定了一份关于急性非癌性疼痛住院成人使用阿片类药物的共识声明,该声明适用于在住院环境中行医的临床医生(例如,医院医师、初级保健医生、家庭医生、执业护士和医师助理)。为了制定共识声明,工作组对相关指南进行了系统审查,根据提取的建议起草了一份声明草案,并从医院阿片类药物处方专家、SHM 成员、SHM 患者家庭咨询委员会、其他专业协会和同行评审员处获得了反馈。经过反复的开发过程,最终形成了一份包含 16 条建议的共识声明,涵盖 1)是否在医院使用阿片类药物,2)如何提高住院期间使用阿片类药物的安全性,以及 3)如何提高出院时阿片类药物处方的安全性。由于共识声明所依据的大多数指南建议仅基于专家意见,因此工作组确定了未来研究的关键问题,以支持循证实践。