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老年人阿片类药物滥用的来源:一项全国代表性调查的结果。

Sources of opioid medication for misuse in older adults: results from a nationally representative survey.

机构信息

Department of Psychology, Texas State University, San Marcos, TX, United States.

Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing and Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, United States.

出版信息

Pain. 2018 Aug;159(8):1543-1549. doi: 10.1097/j.pain.0000000000001241.

Abstract

Despite increasing rates of prescription opioid (PO) misuse in adults 50 years of age and older, little research has investigated such misuse in this population. This work aimed to examine sources of misused opioid medication in adults 50 years and older, with comparisons to younger groups. Data were from the 2009 to 2014 National Survey on Drug Use and Health surveys. Prevalence rates of PO sources, misuse, and PO use disorder (POUD) symptoms were estimated. Design-based logistic regression investigated age-based differences in these factors and the association of sources with POUD symptoms and other concurrent substance use. Nearly half (47.7%) of adults 65 years and older used physician sources for past 30-day PO misuse, with the second highest rates in those 50 to 64 years old (39.2%). Conversely, use of theft (5.3%), purchases (8.5%), or friends/family (for free; 23.2%) to obtain opioids were least common in adults 65 years and older, with prevalence rates of these sources in those 50 years and older closer to those of younger groups. Across those 50 years and older, use of purchases, physician, or multiple sources were associated with elevated POUD symptom prevalence. Older adults, particularly those 65 years and older, use a different pattern of PO sources than adolescents or younger adults, and those using physician sources have elevated POUD symptoms. Physicians are a key avenue for older adults to obtain opioids for misuse, highlighting the potential role of clinicians in limiting such misuse.

摘要

尽管成年人(50 岁及以上)的处方类阿片(PO)滥用率不断上升,但针对这一人群的此类滥用问题的研究却很少。本研究旨在调查 50 岁及以上成年人中,来源不明的阿片类药物滥用的情况,并与年轻人群进行比较。数据来自 2009 年至 2014 年全国药物使用与健康调查。估计了 PO 来源、滥用和 PO 使用障碍(POUD)症状的流行率。基于设计的逻辑回归调查了这些因素在年龄上的差异,以及来源与 POUD 症状和其他同时存在的物质使用之间的关联。近一半(47.7%)65 岁及以上的成年人过去 30 天内曾因医生开具处方而使用 PO 药物,50 至 64 岁的成年人中这一比例排名第二(39.2%)。相反,通过盗窃(5.3%)、购买(8.5%)或从朋友/家人处免费获得(23.2%)阿片类药物的情况在 65 岁及以上的成年人中最为少见,而这一年龄段的成年人使用这些来源的比例更接近年轻群体。在 50 岁及以上的成年人中,使用购买、医生或多种来源与更高的 POUD 症状流行率相关。老年成年人,尤其是 65 岁及以上的成年人,与青少年或年轻成年人相比,使用的 PO 来源模式不同,而使用医生来源的人则有更高的 POUD 症状。医生是老年人获取 PO 药物进行滥用的一个重要途径,这突出了临床医生在限制此类滥用方面的潜在作用。

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