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“球囊无法通过”的冠状动脉慢性完全闭塞病变的介入治疗:还有出路吗?

Interventional Management of "Balloon-Uncrossable" Coronary Chronic Total Occlusion: Is There Any Way Out?

作者信息

Dash Debabrata

机构信息

Thumbay Hospital, Ajman, United Arab Emirates.

Beijing Tiantan Hospital, Beijing, China.

出版信息

Korean Circ J. 2018 Apr;48(4):277-286. doi: 10.4070/kcj.2017.0345.

DOI:10.4070/kcj.2017.0345
PMID:29625510
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5889977/
Abstract

It has been estimated that coronary chronic total occlusion (CTO) is encountered in 15 to 20% patients referred for coronary angiography (CAG). The success of percutaneous coronary intervention (PCI) of CTO can be attributed to the vast array of hardware that has now become available and also to the vastly enhanced operator expertise. It is however realistic to state that despite the tremendous increase in the rate of success, there then comes a subset of CTO where PCI attempts fail. The reason for such failures given that other variables remain constant is the inability to cross the CTO lesion. This can be due to a failure to cross the lesion with a guide wire (despite guide wire escalation). The second cause of failure is the inability to cross the lesion with a balloon (balloon-uncrossable [BU] CTO). This can occur despite the successful placement of a guidewire in the distal true lumen. The BU lesions contribute 2% to 10% of CTO PCI failure cases. The author attempts to present a creative solution to assist crossing such lesions.

摘要

据估计,在接受冠状动脉造影(CAG)的患者中,15%至20%会出现冠状动脉慢性完全闭塞(CTO)。CTO经皮冠状动脉介入治疗(PCI)的成功可归因于现已可用的大量硬件设备以及操作人员专业技能的大幅提升。然而,现实情况是,尽管成功率大幅提高,但仍有一部分CTO患者的PCI尝试会失败。在其他变量保持不变的情况下,此类失败的原因是无法穿过CTO病变。这可能是由于无法用导丝穿过病变(尽管已升级导丝)。失败的第二个原因是无法用球囊穿过病变(球囊无法穿过的[BU]CTO)。尽管导丝已成功置入远端真腔,但仍可能发生这种情况。BU病变占CTO PCI失败病例的2%至10%。作者试图提出一种创新解决方案,以协助穿过此类病变。

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旋磨术(RA)与常规支架置入术治疗慢性完全闭塞(CTO)病变患者的安全性和可行性:系统评价和荟萃分析。
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Efficacy and safety of balloon-assisted microdissection with Sapphire® II 1.0-mm balloon in balloon-uncrossable chronic total occlusion lesions.Sapphire® II 1.0-mm 球囊辅助微切割在球囊不可通过的慢性完全闭塞病变中的疗效和安全性。
J Int Med Res. 2020 Oct;48(10):300060520965822. doi: 10.1177/0300060520965822.
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J Cardiovasc Transl Res. 2020 Apr;13(2):171-180. doi: 10.1007/s12265-019-09917-x. Epub 2020 Jan 29.
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