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艾滋病负担:巴西35年疫情的时间序列分析

The burden of AIDS: a time series analysis of thirty-five years of the epidemic in Brazil.

作者信息

Traebert Jefferson, Traebert Eliane, Schuelter-Trevisol Fabiana, Cortez Escalante Juan Jose, Schneider Ione Jayce Ceola

机构信息

a Programa de Pós-Graduação em Ciências da Saúde , Universidade do Sul de Santa Catarina , Palhoça , Brazil.

b Organizacão Pan-Americana da Saúde/Organizacão Mundial da Saúde , Unidade Técnica de Doenças Transmissíveis e Análise de Situação em Saúde , Brasília , Brazil.

出版信息

AIDS Care. 2018 Nov;30(11):1413-1420. doi: 10.1080/09540121.2018.1456642. Epub 2018 Apr 6.

DOI:10.1080/09540121.2018.1456642
PMID:29625531
Abstract

Although traditional epidemiological information, such as mortality rate and prevalence or incidence rates, is relevant to the understanding of AIDS epidemiology in Brazil, a more complete indicator would be recommended. The aim of this study was to estimate the burden of AIDS and its trends in Brazil from 1980 to 2015. An ecological study using secondary data on mortality, morbidity and demography was carried out. Data were collected from official health information sources. Disability-adjusted life years (DALY) index was estimated by year. Trend analysis of the rates were performed using a segmented linear regression method. There were 826,452 confirmed HIV/AIDS cases and 302,614 deaths from AIDS-related causes in the studied period. The greatest burden occurred between 1994 and 1996, with a significant increase in the burden of AIDS for both sexes. The burden of AIDS in Brazil remains high, with a tendency to increase significantly the DALY rates in the study period. However, trend reversals in the DALY rates and in the mortality component, with a consequent increase in the morbidity component, were identified from 1995 onwards.

摘要

尽管传统的流行病学信息,如死亡率、患病率或发病率,对于理解巴西的艾滋病流行病学情况具有相关性,但还是建议采用一个更全面的指标。本研究的目的是估计1980年至2015年期间巴西艾滋病的负担及其趋势。开展了一项利用死亡率、发病率和人口统计学方面二手数据的生态学研究。数据从官方卫生信息来源收集。按年份估计伤残调整生命年(DALY)指数。使用分段线性回归方法对这些比率进行趋势分析。在研究期间,有826,452例确诊的艾滋病毒/艾滋病病例以及302,614例因艾滋病相关原因导致的死亡。最大负担出现在1994年至1996年期间,男女艾滋病负担均显著增加。巴西的艾滋病负担仍然很高,在研究期间伤残调整生命年率有显著上升的趋势。然而,从1995年起,发现伤残调整生命年率和死亡率组成部分出现趋势逆转,随之发病率组成部分增加。

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