Manabe Yuki, Komatsu Toshiyuki, Seki Shinobu, Sugawara Tatsuya
a Graduate School of Agriculture , Kyoto University , Kyoto , Japan.
b Pharmaceutical and Healthcare Research Laboratories, Research and Development Management Headquarters , FUJIFILM Corporation , Kanagawa , Japan.
Biosci Biotechnol Biochem. 2018 Aug;82(8):1433-1436. doi: 10.1080/09168451.2018.1459467. Epub 2018 Apr 6.
We evaluated the distribution of astaxanthin in rat brains after a single dose administration and after feeding 0.1% astaxanthin diet for 5 days. Astaxanthin was detected in the hippocampus and cerebral cortex 4 and 8 h after a single dose. Astaxanthin concentration in rat brains was higher after consumption of astaxanthin diet for 5 days than after a single dose.
我们评估了单次给药后以及喂食0.1%虾青素饮食5天后虾青素在大鼠大脑中的分布情况。单次给药后4小时和8小时,在海马体和大脑皮层中检测到了虾青素。喂食虾青素饮食5天后大鼠大脑中的虾青素浓度高于单次给药后。