Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
Department of Internal Medicine, Mokpo Hankook Hospital, Mokpo, Korea.
Hepatobiliary Pancreat Dis Int. 2018 Jun;17(3):251-256. doi: 10.1016/j.hbpd.2018.03.014. Epub 2018 Mar 24.
Little information is available about the relationship between restoration of common bile duct (CBD) diameter after endoscopic stone retraction and recurrence of CBD stones in elderly patients. The present study was to determine whether restoration of CBD diameter is a preventive factor for CBD stone recurrence in elderly patients who underwent endoscopic retrograde cholangiopancreatography (ERCP).
From January 2006 to December 2010, 238 patients underwent the first and the second session of ERCP for the removal of CBD stones. Among them, 173 were over 65 years old. These patients were divided into recurrent group and non-recurrent group. Restoration of CBD diameter and patients' characteristics were compared.
There was no statistical difference in patients' characteristics, associated diseases, or ERCP-related complications between the two groups. Reduction of CBD diameter was significantly larger in the non-recurrent group (2.7 ± 1.7 mm) compared to that in the recurrent group (1.4 ± 2.3 mm, P = 0.002). The proportion of patients with restoration of CBD diameter were significantly lower in the recurrent group (6/42, 14.3%) compared with that in the non-recurrent group (67/131, 51.1%) (P < 0.01).
There is an inverse relationship between restoration of CBD diameter and CBD stone recurrence. Therefore, patients without restoration of CBD diameter within 2 weeks after endoscopic stone removal should be monitored more frequently.
关于内镜下取石后胆总管(CBD)直径的恢复与老年患者 CBD 结石复发之间的关系,相关信息较少。本研究旨在确定内镜逆行胰胆管造影(ERCP)后 CBD 直径的恢复是否是老年患者 CBD 结石复发的预防因素。
2006 年 1 月至 2010 年 12 月,238 例患者因 CBD 结石行首次和第二次 ERCP。其中,173 例年龄超过 65 岁。将这些患者分为复发组和非复发组。比较 CBD 直径恢复情况和患者特征。
两组患者的特征、相关疾病或 ERCP 相关并发症均无统计学差异。非复发组 CBD 直径缩小(2.7±1.7mm)明显大于复发组(1.4±2.3mm,P=0.002)。复发组 CBD 直径恢复的患者比例(6/42,14.3%)明显低于非复发组(67/131,51.1%)(P<0.01)。
CBD 直径的恢复与 CBD 结石复发呈负相关。因此,内镜取石后 2 周内 CBD 直径未恢复的患者应更频繁地监测。