Stiris M G, Laerum F
Department of Radiology, Aker University Hospital, Oslo, Norway.
Acta Radiol. 1987 Nov-Dec;28(6):767-70.
A double-blind, cross-over trial of the non-ionic, low-osmolar contrast medium iohexol (Omnipaque) and the ionic, low-osmolar medium ioxaglate (Hexabrix) at concentrations of 300 mg I/ml was carried out in 107 consecutive patients with arterial insufficiency of the lower limbs. The purpose of the study was to observe possible 'carry-over' effects from any of the contrast media, and to evaluate patient discomfort such as pain, adverse reactions, or effect on peripheral blood pressure. No carry-over effect was seen. Ioxaglate caused less injection pain and heat sensations than iohexol, and showed less effect on the systemic blood pressure.
对107例连续性下肢动脉供血不足患者进行了一项双盲交叉试验，比较浓度为300 mg I/ml的非离子型低渗造影剂碘海醇（欧乃派克）和离子型低渗造影剂碘克沙醇（Hexabrix）。本研究的目的是观察任何一种造影剂可能产生的“残留”效应，并评估患者的不适，如疼痛、不良反应或对外周血压的影响。未观察到残留效应。碘克沙醇引起的注射疼痛和热感比碘海醇少，对全身血压的影响也较小。
