He Lei, Xie Peigen, Shu Tao, Liu Zhongyu, Feng Feng, Chen Zihao, Chen Ruiqiang, Zhang Liangming, Rong Limin
Department of Spine Surgery, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Spine Surgery, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
World Neurosurg. 2018 Aug;116:e48-e56. doi: 10.1016/j.wneu.2018.03.193. Epub 2018 Apr 4.
The minimally invasive lateral transpsoas approach allows retroperitoneal access for discectomy and graft placement. However, the procedure has rarely been used for the treatment of septic spondylodiscitis. The purposes of this study were to evaluate the clinical and radiographic outcomes from this minimally invasive procedure for septic spondylodiscitis.
Thirty-one consecutive patients (17 males and 14 females) were included in this study from July 2013 to January 2016. Clinical outcomes were assessed by Oswestry Disability Index, visual analog scale, modified Macnab criteria, and inflammatory parameters. Radiographic results were analyzed by studying the changes in diseased disc height, lordosis, and fusion status.
The Oswestry Disability Index and visual analog scale score improved by 58% and 69% at the last follow-up. The modified Macnab criteria were found to be excellent in 21 patients (68%) and good in 10 (32%). Inflammatory parameters normalized over the average 24 months follow-up. There were no major complications that might have influenced the outcomes in this cohort. A complete fusion after 12 months was achieved in 87% of patients. A mean 7.5 mm restoration in disc height and 6.4° restoration in lumbar lordosis were observed in all patients, whereas an average 4.5 mm loss in restored height resulting from graft subsidence was observed in 24 patients during the follow-up. However, graft subsidence did not influence clinical outcomes significantly.
A minimally invasive lateral transpsoas approach in combination with instrumentation provides a novel treatment for patients with septic spondylodiscitis without severe kyphosis and neurologic impairment.
微创经腰大肌外侧入路可经腹膜后进行椎间盘切除术和植骨。然而,该手术很少用于治疗化脓性脊椎间盘炎。本研究的目的是评估这种微创治疗化脓性脊椎间盘炎的临床和影像学结果。
2013年7月至2016年1月,连续纳入31例患者(男17例,女14例)。通过Oswestry功能障碍指数、视觉模拟评分、改良Macnab标准和炎症参数评估临床结果。通过研究病变椎间盘高度、脊柱前凸和融合状态的变化分析影像学结果。
末次随访时,Oswestry功能障碍指数和视觉模拟评分分别提高了58%和69%。改良Macnab标准评定为优的患者21例(68%),良的患者10例(32%)。炎症参数在平均24个月的随访中恢复正常。该队列中没有可能影响结果的重大并发症。87%的患者在12个月后实现了完全融合。所有患者平均椎间盘高度恢复7.5 mm,腰椎前凸恢复6.4°,而随访期间24例患者因植骨下沉导致恢复高度平均丢失4.5 mm。然而,植骨下沉对临床结果没有显著影响。
微创经腰大肌外侧入路联合内固定为无严重后凸畸形和神经功能障碍的化脓性脊椎间盘炎患者提供了一种新的治疗方法。