Shtaya Anan, Luong Chan Bao, Pereira Erlick
Neurosciences Research Centre, Molecular and Clinical Sciences Research Institute, St. George's University of London, London, United Kingdom; Department of Neurosurgery, Atkinson Morley Wing, St. George's University Hospital, London, United Kingdom.
Department of Neuroanesthesia, Atkinson Morley Wing, St. George's University Hospital, London, United Kingdom.
World Neurosurg. 2018 Jun;114:344-347. doi: 10.1016/j.wneu.2018.03.200. Epub 2018 Apr 5.
Meningioma is a common slow-growing spinal tumor with a predilection for intradural occurrence. Patients usually present with pain followed by ataxia and sensory and sphincter problems. The gold standard treatment in these cases is gross total microsurgical resection under general anesthesia. However, there exist high-anesthetic-risk patients unsuitable for general anesthesia. Performing spinal surgeries under local anesthesia and sedation has been reported, albeit rarely for mostly minimally invasive procedures but not for open intradural pathologies.
We report a 63-year-old woman with critical aortic stenosis, coronary artery disease, and severe chronic obstructive airways disease who presented with 10 months' history of worsening back pain and bilateral leg pain, ataxia, hyperreflexia in lower limbs, as well as altered lower limb sensation. Magnetic resonance imaging revealed a contrast-enhancing intradural lesion at T6/7 with severe spinal cord compression. However, the patient was American Society of Anesthesiologists class IV and her cardiac disease was not amenable to intervention. She underwent thoracic laminectomy and excision of the tumor under local anesthesia and sedation with no significant complications and clinical improvement.
Our illustrative case and literature review suggest that using local anesthesia and sedation to perform spinal surgeries including intradural tumors is possible even in high-risk patients with good outcome. Our American Society of Anesthesiologists class IV patient tolerated the surgery well with gross total tumor resection and subsequent resolution of the symptoms.
脑膜瘤是一种常见的生长缓慢的脊髓肿瘤,好发于硬膜内。患者通常先出现疼痛,随后出现共济失调以及感觉和括约肌问题。这些病例的金标准治疗方法是在全身麻醉下进行全切除显微手术。然而,存在一些不适合全身麻醉的高麻醉风险患者。已有报道在局部麻醉和镇静下进行脊柱手术,尽管大多是针对微创手术,很少用于开放性硬膜内病变。
我们报告一名63岁女性,患有严重主动脉瓣狭窄、冠状动脉疾病和严重慢性阻塞性气道疾病,有10个月来背痛和双侧腿痛加重、共济失调、下肢反射亢进以及下肢感觉改变的病史。磁共振成像显示T6/7水平有一个强化的硬膜内病变,伴有严重脊髓受压。然而,该患者美国麻醉医师协会分级为IV级,其心脏病无法进行干预。她在局部麻醉和镇静下接受了胸椎椎板切除术和肿瘤切除术,未出现明显并发症,临床症状得到改善。
我们的病例及文献回顾表明,即使是高风险患者,使用局部麻醉和镇静进行包括硬膜内肿瘤在内的脊柱手术也是可行的,且效果良好。我们这位美国麻醉医师协会分级为IV级的患者对手术耐受良好,肿瘤实现了全切除,随后症状得到缓解。